NECTIN2
NECTIN2，也稱(chēng)為nectin cell adhesion molecule 2，是一種細(xì)胞粘附分子，屬于免疫球蛋白超家族。它主要在細(xì)胞間粘附和緊密連接的形成與維持中發(fā)揮作用。NECTIN2在T細(xì)胞信號(hào)傳導(dǎo)中具有雙重作用，既能作為CD226的共刺激劑促進(jìn)增殖和細(xì)胞因子產(chǎn)生，也能作為PVRIG的共抑制劑抑制增殖。此外，它還充當(dāng)細(xì)胞粘附蛋白和某些病毒的受體。與NECTIN2相關(guān)的疾病包括多發(fā)性硬化癥等。在藥物研發(fā)方面，針對(duì)NECTIN2的藥物主要針對(duì)癌癥治療，目前已有多個(gè)靶向NECTIN2的藥物處于研發(fā)階段。
熱銷(xiāo)產(chǎn)品
NECTIN2 Antibody (CSB-PA835690LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate, Hela whole cell lysate
All lanes: NECTIN2 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 58, 52 kDa
Observed band size: 58 kDa
NECTIN2 Antibodies
NECTIN2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA019096GA01HU | PVRL2 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA006259 | PVRL2 Antibody | Human | WB, ELISA |
| CSB-PA163325 | PVRL2 Antibody | Human | ELISA,IHC |
| CSB-PA835690LA01HU | NECTIN2 Antibody | Human | ELISA, WB |
| CSB-PA835690LB01HU | NECTIN2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA835690LC01HU | NECTIN2 Antibody, FITC conjugated | Human |
NECTIN2 Proteins
NECTIN2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP019096MO1 CSB-EP019096MO1 CSB-BP019096MO1 CSB-MP019096MO1 CSB-EP019096MO1-B |
Recombinant Mouse Poliovirus receptor-related protein 2 (Pvrl2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF019096MO | Recombinant Mouse Nectin-2 (Nectin2) | in vitro E.coli expression system |
NECTIN2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP835690HU CSB-BP835690HU CSB-MP835690HU CSB-EP835690HU-B |
Recombinant Human Poliovirus receptor-related protein 2 (PVRL2), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP835690HU | Recombinant Human Nectin-2 (PVRL2), partial | E.coli |
| CSB-AP005081HU | Recombinant Human Nectin-2 (NECTIN2), partial (Active) | Mammalian cell |
