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NEU4

NEU4,即神經(jīng)氨酸酶4,別名N-acetyl-alpha-neuraminidase 4。它來(lái)源于生物體內(nèi)的基因編碼,屬于糖水解酶家族,廣泛存在于多種生物體中,包括人類(lèi)和其他哺乳動(dòng)物。NEU4的主要作用機(jī)制是從糖蛋白、糖脂等糖綴合物中去除唾液酸殘基,參與溶酶體內(nèi)唾液酸化糖基共軛物的分解代謝。NEU4通過(guò)調(diào)控細(xì)胞表面的唾液酸水平,影響細(xì)胞的粘附、遷移和信號(hào)傳導(dǎo)等過(guò)程。此外,研究表明NEU4在多種疾病中發(fā)揮著重要作用,如肝癌等癌癥中NEU4的表達(dá)水平與患者的預(yù)后密切相關(guān)。因此,NEU4的研究不僅有助于深入理解細(xì)胞生物學(xué)過(guò)程,還能為相關(guān)疾病的治療提供新的靶點(diǎn)。

熱銷(xiāo)產(chǎn)品

NEU4 Antibody (CSB-PA848831LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA848831LA01HU

IHC image of CSB-PA848831LA01HU diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA848831LA01HU

IHC image of CSB-PA848831LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA848831LA01HU

Immunofluorescence staining of HepG2 cells with CSB-PA848831LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

NEU4 Antibodies

NEU4 for Homo sapiens (Human)

NEU4 Proteins

NEU4 Proteins for Homo sapiens (Human)