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NPRL3

GATOR complex protein NPRL3 is a protein in humans that is encoded by NPRL3 gene. As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

NPRL3 Antibodies

NPRL3 for Homo sapiens (Human)

NPRL3 Proteins

NPRL3 Proteins for Homo sapiens (Human)

NPRL3 Proteins for Mus musculus (Mouse)

NPRL3 Proteins for Drosophila melanogaster (Fruit fly)