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NUMB

Protein numb homolog is a protein in humans that is encoded by NUMB gene. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

NUMB Antibodies

NUMB for Homo sapiens (Human)

NUMB Proteins

NUMB Proteins for Homo sapiens (Human)

NUMB Proteins for Drosophila melanogaster (Fruit fly)

NUMB Proteins for Rattus norvegicus (Rat)

NUMB Proteins for Mus musculus (Mouse)