PCCA
PCCA全稱為丙酰輔酶A羧化酶α亞基，也被稱為丙酰輔酶A羧化酶α鏈。該蛋白是丙酰輔酶A羧化酶復(fù)合物的重要組成部分，該復(fù)合物在丙酸代謝中發(fā)揮關(guān)鍵作用。PCCA蛋白的缺陷會導(dǎo)致丙酸血癥，這是一種罕見的遺傳代謝疾病。目前，針對丙酸血癥的治療主要依賴于肝移植，而mRNA療法如mRNA-3927的研發(fā)為治療該疾病提供了新的希望。此外，PCCA蛋白的研究也為開發(fā)針對其他代謝性疾病的藥物提供了潛在靶點(diǎn)。
熱銷產(chǎn)品
Recombinant Human Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) (CSB-EP017522HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
PCCA Antibody (CSB-PA017522LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: NIH/3T3 whole cell lysate, Hela whole cell lysate
All lanes: PCCA antibody at 4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 81, 78, 76 kDa
Observed band size: 81 kDa
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA017522LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA017522LA01HU at dilution of 1:100
PCCA Antibodies
PCCA for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA017522LA01HU | PCCA Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA017522LB01HU | PCCA Antibody, HRP conjugated | Human | ELISA |
| CSB-PA017522LC01HU | PCCA Antibody, FITC conjugated | Human | |
| CSB-PA017522LD01HU | PCCA Antibody, Biotin conjugated | Human | ELISA |
PCCA Proteins
PCCA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP017522HU CSB-BP017522HU CSB-MP017522HU CSB-EP017522HU-B |
Recombinant Human Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP017522HU | Recombinant Human Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) | E.coli |
