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PCCB

PCCB,全稱為丙酰輔酶A羧化酶β鏈蛋白,也被稱為PCCβ。它在人體內(nèi)參與丙酰輔酶A的合成,對(duì)于氨基酸和脂質(zhì)的分解代謝至關(guān)重要。PCCB蛋白的異??赡軐?dǎo)致丙酸血癥,這是一種罕見(jiàn)的遺傳代謝疾病。目前,針對(duì)PCCB蛋白的研究主要集中在利用基因編輯技術(shù)構(gòu)建基因敲除的細(xì)胞模型,以研究丙酸血癥的發(fā)病機(jī)制。此外,研究人員也在探索通過(guò)補(bǔ)充PCCB蛋白或其相關(guān)藥物來(lái)治療丙酸血癥,以期改善患者的癥狀。

熱銷產(chǎn)品

Recombinant Human Propionyl-CoA carboxylase beta chain, mitochondrial (PCCB) (CSB-EP017523HU)

驗(yàn)證數(shù)據(jù)

CSB-EP017523HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PCCB Antibody (CSB-PA017523LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA017523LA01HU

Western Blot
Positive WB detected in: Jurkat whole cell lysate
All lanes: PCCB antibody at 7.7µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59, 61 kDa
Observed band size: 59 kDa

CSB-PA017523LA01HU

IHC image of CSB-PA017523LA01HU diluted at 1:300 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA017523LA01HU

IHC image of CSB-PA017523LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

PCCB Antibodies

PCCB for Homo sapiens (Human)

PCCB Proteins

PCCB Proteins for Homo sapiens (Human)