PDX1
PDX1，即胰十二指腸同源異形盒1，別名insulinpromoterfactor1、IPF1。它是一種同源盒轉(zhuǎn)錄因子，由人類第5號(hào)染色體上的PDX1基因編碼。PDX1在胰腺發(fā)育及β細(xì)胞功能維持中起重要調(diào)控作用。其作用機(jī)制包括結(jié)合到胰島素基因的啟動(dòng)子上，單獨(dú)或協(xié)同其他因子調(diào)節(jié)胰島素的合成。PDX1對(duì)胰腺發(fā)育、β細(xì)胞成熟與分化、胰島素合成與分泌具有關(guān)鍵作用。PDX1基因的缺失或突變可導(dǎo)致胰腺發(fā)育不全和糖尿病的發(fā)生。PDX1在糖尿病治療中的研究具有重要的應(yīng)用前景和潛在價(jià)值。
熱銷產(chǎn)品
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA068736(PDX1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, Jurkat cells, Primary antibody: CSB-PA068736(PDX1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
PDX1 Antibodies
PDX1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA017746GA01HU | PDX1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA011230 | PDX1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA068736 | PDX1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA114989 | PDX1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
PDX1 Proteins
PDX1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP017746HU CSB-EP017746HU CSB-BP017746HU CSB-MP017746HU CSB-EP017746HU-B |
Recombinant Human Pancreas/duodenum homeobox protein 1 (PDX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
