PIK3R3
PIK3R3，即磷酸肌醇3激酶調(diào)節(jié)亞基3，別名p55、p55PIK。PIK3R3是磷脂酰肌醇3激酶（PI3K）的一個(gè)調(diào)節(jié)亞基，包含兩個(gè)SH2結(jié)構(gòu)域，通過(guò)這些結(jié)構(gòu)域，它能夠結(jié)合激活的蛋白酪氨酸激酶以調(diào)節(jié)其活性。PIK3R3與PI3K的催化亞基結(jié)合，通過(guò)iSH2域與p110催化亞基相互作用，參與細(xì)胞內(nèi)信號(hào)傳導(dǎo)，特別是在生長(zhǎng)因子信號(hào)通路中。PIK3R3在細(xì)胞增殖、腫瘤生長(zhǎng)、炎癥反應(yīng)以及脂質(zhì)代謝中扮演重要角色。PIK3R3的異常表達(dá)與多種癌癥的發(fā)生發(fā)展相關(guān)，包括卵巢癌，并且可能參與調(diào)節(jié)癌癥干細(xì)胞的特性和功能，影響腫瘤的進(jìn)展和化療抗性。
熱銷(xiāo)產(chǎn)品
PIK3R3 Antibody (CSB-PA852884ESR2HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: PIK3R3 antibody at 3.5μg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Jurkat whole cell lysate
Lane 3: Mouse gonadal tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 48, 44 kDa
Observed band size: 55 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA852884ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA852884ESR2HU at dilution of 1:100
PIK3R3 Antibodies
PIK3R3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 種屬反應(yīng)性 | 應(yīng)用類(lèi)型 |
|---|---|---|---|
| CSB-PA018006GA01HU | PIK3R3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA622420 | PIK3R3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA159945 | PIK3R3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA852884ESR1HU | PIK3R3 Antibody | Human | ELISA, IHC |
| CSB-PA852884ESR2HU | PIK3R3 Antibody | Human, Mouse | ELISA, WB, IHC |
PIK3R3 Proteins
PIK3R3 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP018006BO CSB-EP018006BO CSB-BP018006BO CSB-MP018006BO CSB-EP018006BO-B |
Recombinant Bovine Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP727043MO CSB-EP727043MO CSB-BP727043MO CSB-MP727043MO CSB-EP727043MO-B |
Recombinant Mouse Phosphatidylinositol 3-kinase regulatory subunit gamma (Pik3r3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP733971RA CSB-EP733971RA CSB-BP733971RA CSB-MP733971RA CSB-EP733971RA-B |
Recombinant Rat Phosphatidylinositol 3-kinase regulatory subunit gamma (Pik3r3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3R3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱(chēng) | 來(lái)源 |
|---|---|---|
| CSB-YP852884HU CSB-EP852884HU CSB-BP852884HU CSB-MP852884HU CSB-EP852884HU-B |
Recombinant Human Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
