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PLK2

PLK2,即Polo樣激酶2,別名SNK、hSNK、hPlk2。PLK2是一種絲氨酸/蘇氨酸蛋白激酶,屬于Polo樣激酶家族,參與正常細(xì)胞分裂。PLK2在細(xì)胞周期的S期和G2期積累,其蛋白含量和催化活性在有絲分裂開(kāi)始時(shí)達(dá)到峰值,隨后迅速減少。PLK2還參與多個(gè)過(guò)程,包括對(duì)骨髓細(xì)胞凋亡過(guò)程的負(fù)調(diào)控、細(xì)胞衰老的負(fù)調(diào)節(jié)以及參與發(fā)芽血管生成的細(xì)胞遷移的正調(diào)節(jié)。PLK2在多種生理過(guò)程中發(fā)揮作用,包括突觸可塑性、中心體復(fù)制和G1/S期轉(zhuǎn)換,其異常表達(dá)與多種疾病相關(guān),如遺傳性乳腺卵巢癌綜合征和家族性顳葉癲癇2型。

熱銷(xiāo)產(chǎn)品

Recombinant Human Serine/threonine-protein kinase PLK2 (PLK2) (CSB-EP885770HU)

驗(yàn)證數(shù)據(jù)

CSB-EP885770HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

PLK2 Antibody (CSB-PA885770ESR1HU)

驗(yàn)證數(shù)據(jù)

CSB-PA885770ESR1HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA885770ESR1HU at dilution of 1:100

PLK2 Antibodies

PLK2 for Homo sapiens (Human)

PLK2 Proteins

PLK2 Proteins for Mus musculus (Mouse)

PLK2 Proteins for Pongo abelii (Sumatran orangutan)

PLK2 Proteins for Rattus norvegicus (Rat)

PLK2 Proteins for Homo sapiens (Human)