PRMT3
PRMT3，即蛋白質(zhì)精氨酸甲基轉(zhuǎn)移酶3，別名ProteinArginineMethyltransferase3。它是一種由人類基因組編碼的酶，屬于蛋白質(zhì)精氨酸甲基轉(zhuǎn)移酶家族成員之一。PRMT3的作用機(jī)制主要是催化甲基基團(tuán)從S-腺苷甲硫氨酸(SAM)轉(zhuǎn)移到蛋白質(zhì)精氨酸殘基上，形成單甲基化(MMA)和非對(duì)稱二甲基化(ADMA)修飾。這種甲基化修飾能夠調(diào)控多種蛋白質(zhì)的功能，包括轉(zhuǎn)錄因子、核糖體蛋白和信號(hào)轉(zhuǎn)導(dǎo)分子。PRMT3參與調(diào)控細(xì)胞生長(zhǎng)、增殖、分化和基因表達(dá)等重要生物學(xué)過(guò)程。異常的PRMT3表達(dá)或活性與腫瘤、二型糖尿病等疾病的發(fā)生發(fā)展密切相關(guān)。PRMT3通過(guò)精氨酸甲基化修飾相應(yīng)的底物控制著許多重要的細(xì)胞生物學(xué)過(guò)程。
熱銷產(chǎn)品
PRMT3 Antibody (CSB-PA018733LA01HU)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: PRMT3 antibody at 7μg/ml + MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 60, 53 kDa
Observed band size: 53 kDa
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018733LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA018733LA01HU at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using CSB-PA018733LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
PRMT3 Antibodies
PRMT3 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA018733GA01HU | PRMT3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA948631 | PRMT3 Antibody | Human | ELISA,IHC |
| CSB-PA018733LA01HU | PRMT3 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA018733LB01HU | PRMT3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018733LC01HU | PRMT3 Antibody, FITC conjugated | Human | |
| CSB-PA018733LD01HU | PRMT3 Antibody, Biotin conjugated | Human | ELISA |
PRMT3 Proteins
PRMT3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP018733HU CSB-EP018733HU CSB-BP018733HU CSB-MP018733HU CSB-EP018733HU-B |
Recombinant Human Protein arginine N-methyltransferase 3 (PRMT3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
