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RRM2B

Ribonucleoside-diphosphate reductase subunit M2 B is a protein in humans that is encoded by RRM2B gene. Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.

RRM2B Antibodies

RRM2B for Homo sapiens (Human)

RRM2B Proteins

RRM2B Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

RRM2B Proteins for Pongo abelii (Sumatran orangutan)

RRM2B Proteins for Homo sapiens (Human)

RRM2B Proteins for Mus musculus (Mouse)