div class=margin-large-bottom p class=margin-big-bottomSAGE1（Sarcoma Antigen 1）是一種腫瘤睪丸抗原基因，其在多種腫瘤組織中的表達(dá)量通常比癌旁組織高，顯示出與細(xì)胞增生有密切關(guān)系。SAGE1與INTS6（Integrator 6）競爭INTS3（Integrator 3），通過破壞阻礙RNA聚合酶II的“剎車”機(jī)制，新形成的INTS3-SAGE1復(fù)合物與基因靶標(biāo)的啟動(dòng)子-近端區(qū)域結(jié)合，從而激活癌癥相關(guān)途徑中的基因轉(zhuǎn)錄。這一過程最終會(huì)導(dǎo)致細(xì)胞增殖，促進(jìn)腫瘤的生長和擴(kuò)散。SAGE1通過影響細(xì)胞生長、增殖和分化等關(guān)鍵過程的信號(hào)通路，在癌癥的發(fā)生和發(fā)展中發(fā)揮重要作用。p h2 class=margin-large-top熱銷產(chǎn)品h2 pa href=httpswww.pptc.cnRecombinant-ProteinsRecombinant-Human-Sarcoma-antigen-1(SAGE1)--partial-677682.htmlRecombinant Human Sarcoma antigen 1 (SAGE1), partialap div class=card card-5n div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-YP20670HUdiv div class=text-center padding p來源：Yeastp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-EP20670HUdiv div class=text-center padding p來源：E.colip div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-BP20670HUdiv div class=text-center padding p來源：Baculovirusp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-MP20670HUdiv div class=text-center padding p來源：Mammalian cellp div div div class=card-item border margin-big-bottom div class=boldtxt text-center bg-gray-light padding-small head size13CSB-EP20670HU-Bdiv div class=text-center padding p來源：In Vivo Biotinylation in E.colip div div div div br