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SEMA3A

SEMA3A,全名為Semaphorin-3A,常見(jiàn)別名包括COLL1、COLLAPSIN 1、SEMAIII、SEMAPHORIN L等。該蛋白在生長(zhǎng)錐引導(dǎo)中發(fā)揮重要作用,可能通過(guò)選擇性排斥終止于背側(cè)的軸突來(lái)模式化感覺(jué)投射。它參與嗅覺(jué)系統(tǒng)的發(fā)育和青春期神經(jīng)元控制,對(duì)神經(jīng)系統(tǒng)的正常功能至關(guān)重要。SEMA3A與多種疾病相關(guān),如骨關(guān)節(jié)炎,研究表明其在疾病進(jìn)展中具有軟骨保護(hù)作用。此外,該蛋白還與神經(jīng)發(fā)育障礙和腫瘤轉(zhuǎn)移等疾病有關(guān)。在藥物研發(fā)方面,針對(duì)SEMA3A的靶向治療正在探索中,以期用于治療神經(jīng)系統(tǒng)疾病和癌癥等。目前已有重組小鼠SEMA3A蛋白等生物試劑可用于科研實(shí)驗(yàn),為深入研究其功能和應(yīng)用提供了便利。

熱銷產(chǎn)品

SEMA3A Antibody (CSB-PA613506LA01HU)

驗(yàn)證數(shù)據(jù)

CSB-PA613506LA01HU

Western Blot
Positive WB detected in: Hela whole cell lysate, 293 whole cell lysate, Rat kidney tissue, Mouse heart tissue, Mouse skeletal muscle tissue
All lanes: SEMA3A antibody at 3.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 89 kDa
Observed band size: 89 kDa

CSB-PA613506LA01HU

IHC image of CSB-PA613506LA01HU diluted at 1:300 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA613506LA01HU

IHC image of CSB-PA613506LA01HU diluted at 1:300 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated ABC system.

Human Semaphorin 3A(Sema 3A)ELISA Kit (CSB-E15913h)

驗(yàn)證數(shù)據(jù)

CSB-E15913h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E15913h

規(guī)格:96T/48T

靈敏度:0.039 ng/mL

檢測(cè)范圍:0.156 ng/mL-10 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

SEMA3A Antibodies

SEMA3A for Homo sapiens (Human)

SEMA3A Proteins

SEMA3A Proteins for Homo sapiens (Human)

SEMA3A ELISA Kit

SEMA3A ELISA Kit for Homo sapiens (Human)