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SERPINF2

SERPINF2,全名為alpha-2-antiplasmin isoform a precursor,常見別名為A2AP、AAP、ALPHA-2-PI、API、PLI。該蛋白是纖溶系統(tǒng)中的核心調(diào)控分子,主要作用是抑制纖溶酶的活性,從而防止過度纖維蛋白溶解并確保血栓穩(wěn)定。在血液中循環(huán)時(shí),它可以與纖溶酶結(jié)合,阻止其降解纖維蛋白,維持血液凝固的平衡。相關(guān)疾病方面,SERPINF2蛋白的缺乏或功能異??赡軐?dǎo)致alpha-2-抗纖溶酶缺乏癥,這是一種嚴(yán)重的出血性疾病,患者會出現(xiàn)嚴(yán)重的出血傾向。在藥物研發(fā)方面,由于該蛋白在血液凝固中起著重要作用,因此針對SERPINF2蛋白的藥物研發(fā)主要集中在血栓性疾病和出血性疾病的治療上。例如,一些藥物可以增強(qiáng)SERPINF2蛋白的活性,從而促進(jìn)血栓形成,用于治療缺血性心臟病等疾病;另一些藥物則可以抑制SERPINF2蛋白的活性,用于治療出血性疾病。

熱銷產(chǎn)品

SERPINF2 Antibody (CSB-PA294574)

驗(yàn)證數(shù)據(jù)

CSB-PA294574

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA294574(SERPINF2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA294574

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human normal stomach tissue, Primary antibody: CSB-PA294574(SERPINF2 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds

Human α2-Antiplasmin,α2-AP ELISA Kit (CSB-E09452h)

驗(yàn)證數(shù)據(jù)

CSB-E09452h 標(biāo)準(zhǔn)曲線

貨號:CSB-E09452h

規(guī)格:96T/48T

靈敏度:3.9 pg/mL

檢測范圍:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

SERPINF2 Antibodies

SERPINF2 for Homo sapiens (Human)

SERPINF2 Proteins

SERPINF2 Proteins for Bos taurus (Bovine)

SERPINF2 Proteins for Homo sapiens (Human)

SERPINF2 Proteins for Struthio camelus (Ostrich)

SERPINF2 Proteins for Mus musculus (Mouse)

SERPINF2 ELISA Kit

SERPINF2 ELISA Kit for Homo sapiens (Human)