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SFTPD

SFTPD,即肺表面活性蛋白D,別名SP-D、COLEC7。它是一種重要的免疫調(diào)節(jié)蛋白,屬于膠原凝集素家族成員,主要在肺泡襯細(xì)胞和與管狀結(jié)構(gòu)相關(guān)的上皮細(xì)胞中組成性分泌,同時(shí)也在心臟平滑肌和內(nèi)皮細(xì)胞中誘導(dǎo)表達(dá)。SFTPD在血清、血漿、支氣管肺泡灌洗液和羊水中均有存在。其作用機(jī)制涉及結(jié)合中性粒細(xì)胞防御素,調(diào)節(jié)抗病毒防御,以及參與機(jī)體防御和先天性免疫。SFTPD通過(guò)識(shí)別和結(jié)合多種病原體,促進(jìn)病原體的吞噬作用,同時(shí)調(diào)節(jié)炎癥反應(yīng),維持肺部穩(wěn)態(tài)。SFTPD在防御肺部感染、調(diào)節(jié)免疫反應(yīng)以及肺泡穩(wěn)態(tài)中發(fā)揮著重要作用,其異常表達(dá)與多種肺部疾病的發(fā)生發(fā)展相關(guān),包括哮喘、肺疾病(多種)、呼吸道合胞體病毒感染性疾病和鼻炎等。

熱銷(xiāo)產(chǎn)品

Recombinant Human Pulmonary surfactant-associated protein D (SFTPD) (CSB-YP021175HU)

驗(yàn)證數(shù)據(jù)

CSB-YP021175HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-YP021175HU

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP021175HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) SFTPD.

CSB-YP021175HU

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP021175HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) SFTPD.

SFTPD Antibody (CSB-PA924520)

驗(yàn)證數(shù)據(jù)

CSB-PA924520

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA924520(SFTPD Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA924520

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA924520(SFTPD Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

Human Pulmonary surfactant-associated protein D,SP-D ELISA Kit (CSB-E11166h)

驗(yàn)證數(shù)據(jù)

CSB-E11166h 標(biāo)準(zhǔn)曲線(xiàn)

貨號(hào):CSB-E11166h

規(guī)格:96T/48T

靈敏度:0.31 ng/mL

檢測(cè)范圍:1.25 ng/mL-80 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

SFTPD Antibodies

SFTPD for Homo sapiens (Human)

SFTPD Proteins

SFTPD Proteins for Homo sapiens (Human)

SFTPD ELISA Kit

SFTPD ELISA Kit for Homo sapiens (Human)