SLC16A11
SLC16A11，即溶質(zhì)載體家族16成員11，別名MCT11。SLC16A11是一種單羧酸轉(zhuǎn)運蛋白，負責丙酮酸的跨膜轉(zhuǎn)運，參與脂質(zhì)代謝過程，并位于內(nèi)質(zhì)網(wǎng)膜和質(zhì)膜上。SLC16A11通過質(zhì)子耦聯(lián)機制轉(zhuǎn)運單羧酸類物質(zhì)，包括丙酮酸、乳酸、酮體和短鏈脂肪酸，其轉(zhuǎn)運方向由細胞膜兩側(cè)的質(zhì)子和單羧酸鹽濃度梯度決定。SLC16A11的功能異常與多種疾病相關(guān)，如2型糖尿病、胰島素抵抗和血脂代謝異常。SLC16A11在肝臟中表達，其變異可能通過影響肝臟細胞的乳酸轉(zhuǎn)運和甘油三酯代謝功能，進而影響糖尿病的發(fā)生和發(fā)展。
熱銷產(chǎn)品
SLC16A11 Antibody (CSB-PA843323LA01HU)
驗證數(shù)據(jù)
Western Blot
Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate
All lanes: SLC16A11 antibody at 3.8µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 48 kDa
Observed band size: 48 kDa
Immunofluorescence staining of A549 cells with CSB-PA843323LA01HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SLC16A11 Antibodies
SLC16A11 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA808680 | SLC16A11 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA371613 | SLC16A11 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA843323LA01HU | SLC16A11 Antibody | Human | ELISA, WB, IF |
| CSB-PA843323LB01HU | SLC16A11 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA843323LC01HU | SLC16A11 Antibody, FITC conjugated | Human | |
| CSB-PA843323LD01HU | SLC16A11 Antibody, Biotin conjugated | Human | ELISA |
SLC16A11 Proteins
SLC16A11 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP843323HU CSB-EP843323HU CSB-BP843323HU CSB-MP843323HU CSB-EP843323HU-B |
Recombinant Human Monocarboxylate transporter 11 (SLC16A11), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
