SOCS3

SOCS3，即細(xì)胞因子信號(hào)傳導(dǎo)抑制因子3，別名EF10、EF-10、CISH3、SSI3、CIS-3、SOCS-3、ATOD4、MGC71791等。SOCS3由人類SOCS3基因編碼，該基因廣泛表達(dá)于多種組織中。SOCS3主要通過(guò)與JAK/STAT信號(hào)通路中的酪氨酸激酶受體結(jié)合，抑制其活性，從而負(fù)向調(diào)節(jié)細(xì)胞因子信號(hào)傳導(dǎo)。它能夠抑制包括gp130、LIF、促紅細(xì)胞生成素、胰島素、IL12、GCSF和瘦素受體在內(nèi)的多種細(xì)胞因子信號(hào)傳導(dǎo)。SOCS3參與調(diào)節(jié)免疫反應(yīng)、炎癥過(guò)程以及代謝過(guò)程，對(duì)于維持機(jī)體免疫平衡和抑制腫瘤生長(zhǎng)具有重要作用。SOCS3的異常表達(dá)與多種疾病相關(guān)，包括腫瘤、自身免疫性疾病和代謝性疾病。

熱銷產(chǎn)品

SOCS3 Antibody (CSB-PA022392EA01HU)

驗(yàn)證數(shù)據(jù)

Immunocytochemistry analysis of human liver cancer using CSB-PA022392EA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA022392EA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

SOCS3 Antibody

SOCS3 Protein

SOCS3 ELISA Kit

SOCS3 Antibodies

SOCS3 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA022392GA01HU	SOCS3 Antibody	Human,Mouse,Rat	ELISA,WB,IHC,IF
CSB-PA938450	SOCS3 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA957037	SOCS3 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA022392EA01HU	SOCS3 Antibody	Human	ELISA, IHC, IF
CSB-PA022392EB01HU	SOCS3 Antibody, HRP conjugated	Human	ELISA
CSB-PA022392EC01HU	SOCS3 Antibody, FITC conjugated	Human
CSB-PA022392ED01HU	SOCS3 Antibody, Biotin conjugated	Human	ELISA

SOCS3 for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA022392LA01RA	Socs3 Antibody	Rat, Human	ELISA, WB
CSB-PA022392LD01RA	Socs3 Antibody, Biotin conjugated	Rat	ELISA
CSB-PA022392LC01RA	Socs3 Antibody, FITC conjugated	Rat
CSB-PA022392LB01RA	Socs3 Antibody, HRP conjugated	Rat	ELISA

SOCS3 Proteins

SOCS3 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP022392HU CSB-EP022392HU CSB-BP022392HU CSB-MP022392HU CSB-EP022392HU-B	Recombinant Human Suppressor of cytokine signaling 3 (SOCS3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SOCS3 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP022392MO CSB-EP022392MO CSB-BP022392MO CSB-MP022392MO CSB-EP022392MO-B	Recombinant Mouse Suppressor of cytokine signaling 3 (Socs3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SOCS3 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP022392RA	Recombinant Rat Suppressor of cytokine signaling 3 (Socs3)	Yeast
CSB-EP022392RA	Recombinant Rat Suppressor of cytokine signaling 3 (Socs3)	E.coli
CSB-BP022392RA CSB-MP022392RA CSB-EP022392RA-B	Recombinant Rat Suppressor of cytokine signaling 3 (Socs3)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SOCS3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP022392DO CSB-EP022392DO CSB-BP022392DO CSB-MP022392DO CSB-EP022392DO-B	Recombinant Dog Suppressor of cytokine signaling 3 (SOCS3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SOCS3 Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP022392CH CSB-EP022392CH CSB-BP022392CH CSB-MP022392CH CSB-EP022392CH-B	Recombinant Chicken Suppressor of cytokine signaling 3 (SOCS3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SOCS3 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP022392BO CSB-EP022392BO CSB-BP022392BO CSB-MP022392BO CSB-EP022392BO-B	Recombinant Bovine Suppressor of cytokine signaling 3 (SOCS3)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli