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STAMBP

STAM-binding protein is a protein in humans that is encoded by STAMBP gene. Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes.

STAMBP Antibodies

STAMBP for Homo sapiens (Human)

STAMBP Proteins

STAMBP Proteins for Homo sapiens (Human)

STAMBP Proteins for Xenopus laevis (African clawed frog)

STAMBP Proteins for Rattus norvegicus (Rat)

STAMBP Proteins for Mus musculus (Mouse)