TAGLN2

TAGLN2，即轉(zhuǎn)膠蛋白2，別名HA1756、Transgelin-2。它是一種肌動蛋白細(xì)胞骨架結(jié)合蛋白家族的重要成員，廣泛表達(dá)于多種組織細(xì)胞中。
TAGLN2的作用機(jī)制涉及調(diào)節(jié)細(xì)胞形態(tài)、運(yùn)動和細(xì)胞轉(zhuǎn)化，通過直接結(jié)合肌動蛋白微絲結(jié)構(gòu)影響細(xì)胞骨架的重塑，進(jìn)而參與細(xì)胞形態(tài)轉(zhuǎn)化、細(xì)胞遷移運(yùn)動、細(xì)胞分化及增殖凋亡等功能調(diào)控。
TAGLN2在腫瘤細(xì)胞惡性表型中的潛在功能受到研究者關(guān)注，它不僅與肌動蛋白骨架緊密連接調(diào)控細(xì)胞運(yùn)動，還在細(xì)胞核中表達(dá)，可能通過直接調(diào)控相關(guān)基因的表達(dá)而影響細(xì)胞表型。TAGLN2的表達(dá)增加與腫瘤等級升高、預(yù)后不良相關(guān)，其在腫瘤發(fā)展中的作用使其成為潛在的分子治療靶點(diǎn)。

熱銷產(chǎn)品

Recombinant Human Transgelin-2 (TAGLN2) (CSB-EP023106HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP023106HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TAGLN2.

TAGLN2 Antibody (CSB-PA023106DSR1HU)

驗(yàn)證數(shù)據(jù)

Western blot
All lanes: TAGLN2 antibody at 4.04µg/ml
Lane 1: 293T whole cell lysate
Lane 2: K562 whole cell lysate
Lane 3: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 23, 25 kDa
Observed band size: 23 kDa

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023106DSR1HU at dilution of 1:100

Human Transgelin-2(TAGLN2) ELISA kit (CSB-EL023106HU)

驗(yàn)證數(shù)據(jù)

貨號：CSB-EL023106HU

規(guī)格：96T/48T

靈敏度：0.078 ng/mL

檢測范圍：0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TAGLN2 Antibody

TAGLN2 Protein

TAGLN2 ELISA Kit

TAGLN2 Antibodies

TAGLN2 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA023106GA01HU	TAGLN2 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA209872	TAGLN2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA121037	TAGLN2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA023106DSR1HU	TAGLN2 Antibody	Human	ELISA, WB, IHC
CSB-PA023106DSR2HU	TAGLN2 Antibody	Human	ELISA, WB, IHC

TAGLN2 Proteins

TAGLN2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023106HU CSB-BP023106HU CSB-MP023106HU CSB-EP023106HU-B	Recombinant Human Transgelin-2 (TAGLN2)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP023106HU	Recombinant Human Transgelin-2 (TAGLN2)	E.coli
CSB-EP023106HUa0	Recombinant Human Transgelin-2 (TAGLN2)	E.coli