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TAOK2

Serine/threonine-protein kinase TAO2 is a protein in humans that is encoded by TAOK2 gene. Serine/threonine-protein kinase involved in different processes such as membrane blebbing and apoptotic bodies formation DNA damage response and MAPK14/p38 MAPK stress-activated MAPK cascade. Phosphorylates itself, MBP, activated MAPK8, MAP2K3, MAP2K6 and tubulins. Activates the MAPK14/p38 MAPK signaling pathway through the specific activation and phosphorylation of the upstream MAP2K3 and MAP2K6 kinases. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Isoform 1, but not isoform 2, plays a role in apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation.

TAOK2 Antibodies

TAOK2 for Homo sapiens (Human)

TAOK2 Proteins

TAOK2 Proteins for Mus musculus (Mouse)

TAOK2 Proteins for Xenopus laevis (African clawed frog)

TAOK2 Proteins for Rattus norvegicus (Rat)

TAOK2 Proteins for Homo sapiens (Human)