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TCAP

TCAP,別名Telethonin、T-cap、LGMD2G、LGMDR7等,是一種由人類TCAP基因編碼的蛋白質(zhì),主要在橫紋肌和心肌中表達(dá),與肌肉的結(jié)構(gòu)和功能密切相關(guān)。
TCAP可以與肌聯(lián)蛋白的Z1-Z2結(jié)構(gòu)域結(jié)合,作為肌聯(lián)蛋白激酶的底物,對(duì)肌節(jié)組裝至關(guān)重要。TCAP基因的突變與四肢帶型肌營(yíng)養(yǎng)不良2G(LGMD2G)和心肌病有關(guān)。TCAP在維持肌肉結(jié)構(gòu)完整性和功能中發(fā)揮重要作用,其異常表達(dá)或功能喪失可能導(dǎo)致肌肉疾病,包括肌營(yíng)養(yǎng)不良和心肌癥。

熱銷產(chǎn)品

Recombinant Human Telethonin (TCAP) (CSB-EP023264HU)

驗(yàn)證數(shù)據(jù)

CSB-EP023264HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TCAP Antibody (CSB-PA023264ESR1HU)

驗(yàn)證數(shù)據(jù)

CSB-PA023264ESR1HU

Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA023264ESR1HU at dilution of 1:100

CSB-PA023264ESR1HU

Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA023264ESR1HU at dilution of 1:100

TCAP Antibodies

TCAP for Homo sapiens (Human)

TCAP Proteins

TCAP Proteins for Homo sapiens (Human)