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TDO2

TDO2，即色氨酸2,3-雙加氧酶，別名TO、TDO、TPH2、TRPO、HYPTRP。TDO2由人類TDO2基因編碼，該基因位于4號(hào)染色體的q32.1區(qū)域。TDO2是一種血紅素酶，在色氨酸代謝中發(fā)揮關(guān)鍵作用，通過(guò)催化犬尿氨酸途徑的第一步和限速步驟，將色氨酸轉(zhuǎn)化為犬尿氨酸。TDO2的活性增加和隨后犬尿氨酸的產(chǎn)生可能通過(guò)抑制抗腫瘤免疫反應(yīng)在癌癥中發(fā)揮作用，且該基因中的單核苷酸多態(tài)性可能與自閉癥有關(guān)。TDO2在調(diào)節(jié)全身的色氨酸水平中起關(guān)鍵作用，并在癌癥免疫學(xué)中具有重要作用。

熱銷產(chǎn)品

Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) (CSB-EP023351HU)

驗(yàn)證數(shù)據(jù)

CSB-EP023351HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TDO2 Proteins

TDO2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào) 產(chǎn)品名稱 來(lái)源
CSB-YP023351HU Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) Yeast
CSB-EP023351HU Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) E.coli
CSB-BP023351HU
CSB-MP023351HU
CSB-EP023351HU-B
 Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) Baculovirus
Mammalian cell
In Vivo Biotinylation in E.coli
CSB-EP023351HUb2 Recombinant Human Tryptophan 2,3-dioxygenase (TDO2) E.coli