TERT

TERT，即端粒酶反轉錄酶，是端粒酶的核心亞基，由多個結構域組成，包括端粒酶保守基序結構域、催化域和RNA結合域等。它負責在細胞分裂過程中，通過反轉錄機制將RNA模板轉錄成DNA，并添加到染色體末端的端粒DNA序列中，從而維持端粒長度，確保細胞的持續(xù)增殖能力。TERT的表達受到嚴格調控，但在腫瘤細胞中常異常上調，與腫瘤的發(fā)生和發(fā)展密切相關。除了維持端粒長度，TERT還參與DNA修復、細胞存活、防止凋亡、促進生長和增殖等過程，并展現(xiàn)出獨立于端粒的新生物學功能，如基因轉錄調控、血管新生和免疫炎癥等。這些發(fā)現(xiàn)不僅為理解TERT的生物學作用提供了新的視角，也為治療端粒酶相關疾病提供了重要的理論基礎和潛在的治療策略。

熱銷產品

Recombinant Human Telomerase reverse transcriptase (TERT), partial (CSB-EP023391HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TERT Antibody

TERT Protein

TERT ELISA Kit

TERT Antibodies

TERT for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA10669A0Rb	TERT Antibody	Human	ELISA, IHC
CSB-PA10669C0Rb	TERT Antibody, FITC conjugated	Human
CSB-PA10669B0Rb	TERT Antibody, HRP conjugated	Human	ELISA
CSB-PA10669D0Rb	TERT Antibody, Biotin conjugated	Human	ELISA
CSB-PA004257	TERT Antibody	Human	WB, IF, ELISA
CSB-PA006014	TERT Antibody	Human	WB, ELISA
CSB-PA050241	Phospho-TERT (S824) Antibody	Human	WB, IHC, ELISA
CSB-PA050242	Phospho-TERT (S227) Antibody	Human	IF, ELISA
CSB-PA912041	TERT Antibody	Human	ELISA,WB,IHC
CSB-PA199893	TERT Antibody	Human	ELISA,WB
CSB-PA257364	TERT Antibody	Human	ELISA,IHC
CSB-PA585649	TERT Antibody	Human	ELISA,IHC
CSB-PA232517	TERT Antibody	Human	WB, IHC, ELISA
CSB-RA798840A0HU	TERT Recombinant Monoclonal Antibody	Human	ELISA, IHC

TERT Proteins

TERT Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP023391HU CSB-BP023391HU CSB-MP023391HU CSB-EP023391HU-B	Recombinant Human Telomerase reverse transcriptase (TERT), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP023391HU	Recombinant Human Telomerase reverse transcriptase (TERT), partial	E.coli