TIPARP
TIPARP,即TCDD誘導(dǎo)型聚(ADP-核糖)聚合酶,別名PARP7、ARTD14、pART14。TIPARP由人類TIPARP基因編碼,該基因位于3號(hào)染色體的q25.31區(qū)域。TIPARP是一種聚(ADP-核糖)聚合酶超家族的成員,它使用NAD+作為底物,將ADP-核糖轉(zhuǎn)移到蛋白質(zhì)受體的谷氨酸殘基上;反復(fù)的ADP-核糖基化作用導(dǎo)致在蛋白質(zhì)上形成聚鏈,從而改變目標(biāo)蛋白的功能。TIPARP在多種生理過程中發(fā)揮作用,包括基因調(diào)控、病毒響應(yīng)和細(xì)胞骨架調(diào)控。TIPARP的異常調(diào)控可能引起神經(jīng)發(fā)育障礙、異常的抗病毒反應(yīng)、某些類型的癌癥以及二惡英誘導(dǎo)的肝脂肪變性。
熱銷產(chǎn)品
Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) (CSB-BP801800HU)
驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TIPARP Antibody (CSB-PA801800LA01HU)
驗(yàn)證數(shù)據(jù)

Western Blot
Positive WB detected in: U87 whole cell lysate, SH-SY5Y whole cell lysate
All lanes: TIPARP antibody at 4.6µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 77 kDa
Observed band size: 77 kDa

IHC image of CSB-PA801800LA01HU diluted at 1:300 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA801800LA01HU diluted at 1:300 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
TIPARP Antibodies
TIPARP for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
---|---|---|---|
CSB-PA797551 | TIPARP Antibody | Human,Mouse | ELISA,WB |
CSB-PA801800LA01HU | TIPARP Antibody | Human | ELISA, WB, IHC |
CSB-PA801800LB01HU | TIPARP Antibody, HRP conjugated | Human | ELISA |
CSB-PA801800LC01HU | TIPARP Antibody, FITC conjugated | Human | |
CSB-PA801800LD01HU | TIPARP Antibody, Biotin conjugated | Human | ELISA |
TIPARP Proteins
TIPARP Proteins for Homo sapiens (Human)
產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
---|---|---|
CSB-YP801800HU CSB-MP801800HU CSB-EP801800HU-B |
Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP801800HU | Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) | E.coli |
CSB-BP801800HU | Recombinant Human Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) | Baculovirus |