TLR2

TLR2，全稱Toll樣受體2，是一種重要的免疫識別蛋白，也被稱為CD284。它參與人體對病原體的識別和免疫反應(yīng)，在急性炎癥、細(xì)胞信號轉(zhuǎn)導(dǎo)和細(xì)胞凋亡中發(fā)揮關(guān)鍵作用。TLR2通常與LY96蛋白協(xié)同工作，識別細(xì)菌的脂蛋白和細(xì)胞壁成分，啟動免疫應(yīng)答。其激活后可引發(fā)多種信號通路，如NF-κB和MAPK通路，進(jìn)而調(diào)節(jié)炎癥因子如TNF-α和IL-1的分泌。TLR2與多種疾病的發(fā)生發(fā)展密切相關(guān)，包括類風(fēng)濕性關(guān)節(jié)炎、紅斑狼瘡、糖尿病和心血管疾病等。針對TLR2的藥物研發(fā)已成為熱點(diǎn)，例如清華大學(xué)尹航團(tuán)隊研發(fā)的小分子CU-T12-9可作為Toll樣受體調(diào)節(jié)劑，用于開發(fā)治療類風(fēng)濕性關(guān)節(jié)炎和紅斑狼瘡等免疫疾病的疫苗。此外，TLR2拮抗劑的研究也取得進(jìn)展，有望為心血管疾病等提供新的治療策略。

熱銷產(chǎn)品

Recombinant Human Toll-like receptor 2 (TLR2), partial (CSB-EP023601HU1)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP023601HU1 could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TLR2.

TLR2 Antibody (CSB-PA205006)

驗(yàn)證數(shù)據(jù)

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA205006(TLR2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)

Human toll-like receptor 2,TLR2 ELISA Kit (CSB-E11781h)

驗(yàn)證數(shù)據(jù)

貨號：CSB-E11781h

規(guī)格：96T/48T

靈敏度：0.078 ng/mL

檢測范圍：0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TLR2 Antibody

TLR2 Protein

TLR2 ELISA Kit

TLR2 Antibodies

TLR2 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA023601LD01HU	TLR2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA023601LC01HU	TLR2 Antibody, FITC conjugated	Human
CSB-PA023601LB01HU	TLR2 Antibody, HRP conjugated	Human	ELISA
CSB-PA023601LA01HU	TLR2 Antibody	Human	ELISA
CSB-PA080185	TLR2 Antibody	Human,Mouse,Rat	IHC, ELISA
CSB-PA205006	TLR2 Antibody	Human,Mouse	ELISA,IHC
CSB-PA183593	TLR2 Antibody	Human,Mouse	ELISA,IHC

TLR2 Proteins

TLR2 Proteins for Ovis aries (Sheep)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601SH1 CSB-EP023601SH1 CSB-BP023601SH1 CSB-MP023601SH1 CSB-EP023601SH1-B	Recombinant Sheep Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601SH	Recombinant Sheep Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Macaca mulatta (Rhesus macaque)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601MOW1 CSB-EP023601MOW1 CSB-BP023601MOW1 CSB-MP023601MOW1 CSB-EP023601MOW1-B	Recombinant Macaca mulatta (Rhesus macaque) Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601MOW	Recombinant Macaca mulatta (Rhesus macaque) Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Giraffa camelopardalis (Giraffe)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601GGC1 CSB-EP023601GGC1 CSB-BP023601GGC1 CSB-MP023601GGC1 CSB-EP023601GGC1-B	Recombinant Giraffa camelopardalis Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601GGC	Recombinant Giraffa camelopardalis Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Gorilla gorilla gorilla (Lowland gorilla)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601GGZ1 CSB-EP023601GGZ1 CSB-BP023601GGZ1 CSB-MP023601GGZ1 CSB-EP023601GGZ1-B	Recombinant Gorilla gorilla gorilla Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601GGZ	Recombinant Gorilla gorilla gorilla Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Capra ibex (Ibex)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601CZZ1 CSB-EP023601CZZ1 CSB-BP023601CZZ1 CSB-MP023601CZZ1 CSB-EP023601CZZ1-B	Recombinant Capra ibex Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601CZZ	Recombinant Capra ibex Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Bison bison (American bison) (Bos bison)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601BTE1 CSB-EP023601BTE1 CSB-BP023601BTE1 CSB-MP023601BTE1 CSB-EP023601BTE1-B	Recombinant Bison bison Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601BTE	Recombinant Bison bison Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Pan troglodytes (Chimpanzee)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601EQV1 CSB-EP023601EQV1 CSB-BP023601EQV1 CSB-MP023601EQV1 CSB-EP023601EQV1-B	Recombinant Pan troglodytes Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601EQV	Recombinant Pan troglodytes Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Pan paniscus (Pygmy chimpanzee) (Bonobo)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601EQU1 CSB-EP023601EQU1 CSB-BP023601EQU1 CSB-MP023601EQU1 CSB-EP023601EQU1-B	Recombinant Pan paniscus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601EQU	Recombinant Pan paniscus Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Bos indicus (Zebu)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601BUL1 CSB-EP023601BUL1 CSB-BP023601BUL1 CSB-MP023601BUL1 CSB-EP023601BUL1-B	Recombinant Bos indicus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF023601BUL	Recombinant Bos indicus Toll-like receptor 2 (TLR2)	in vitro E.coli expression system

TLR2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601DO CSB-EP023601DO CSB-BP023601DO CSB-MP023601DO CSB-EP023601DO-B	Recombinant Dog Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Equus caballus (Horse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601HO CSB-EP023601HO CSB-BP023601HO CSB-MP023601HO CSB-EP023601HO-B	Recombinant Horse Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601BO CSB-EP023601BO CSB-BP023601BO CSB-MP023601BO CSB-EP023601BO-B	Recombinant Bovine Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601MOV CSB-EP023601MOV CSB-BP023601MOV CSB-MP023601MOV CSB-EP023601MOV-B	Recombinant Macaca fascicularis Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601DXU CSB-EP023601DXU CSB-BP023601DXU CSB-MP023601DXU CSB-EP023601DXU-B	Recombinant Cricetulus griseus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601MO CSB-EP023601MO CSB-BP023601MO CSB-MP023601MO CSB-EP023601MO-B	Recombinant Mouse Toll-like receptor 2 (Tlr2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Capra hircus (Goat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601GO CSB-EP023601GO CSB-BP023601GO CSB-MP023601GO CSB-EP023601GO-B	Recombinant Goat Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Bubalus bubalis (Domestic water buffalo)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601BWX CSB-EP023601BWX CSB-BP023601BWX CSB-MP023601BWX CSB-EP023601BWX-B	Recombinant Bubalus bubalis Toll-like receptor 2 (TLR2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Boselaphus tragocamelus (Nilgai)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023601BUN CSB-EP023601BUN CSB-BP023601BUN CSB-MP023601BUN CSB-EP023601BUN-B	Recombinant Boselaphus tragocamelus Toll-like receptor 2 (TLR2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TLR2 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-EP023601HU1	Recombinant Human Toll-like receptor 2 (TLR2), partial	E.coli
CSB-CF023601HU	Recombinant Human Toll-like receptor 2 (TLR2)	in vitro E.coli expression system