TNC

TNC，即神經(jīng)膠質(zhì)素C，別名Tenascin-C、TN，是一種廣泛分布于細(xì)胞外基質(zhì)中的大型糖蛋白，主要由成纖維細(xì)胞、內(nèi)皮細(xì)胞和平滑肌細(xì)胞等分泌。TNC具有獨(dú)特的多域結(jié)構(gòu)，能夠與多種細(xì)胞表面受體（如整合素、Notch受體）及其它細(xì)胞外基質(zhì)成分相互作用，通過調(diào)節(jié)細(xì)胞粘附、遷移、增殖和分化等過程，參與組織的發(fā)育、重塑及修復(fù)。在生理狀態(tài)下，TNC對于維持組織穩(wěn)態(tài)和促進(jìn)傷口愈合具有重要作用。然而，在病理?xiàng)l件下，如腫瘤發(fā)生發(fā)展過程中，TNC的異常高表達(dá)可促進(jìn)癌細(xì)胞的侵襲和轉(zhuǎn)移，參與構(gòu)建有利于腫瘤生長的微環(huán)境，成為疾病進(jìn)展的關(guān)鍵因素之一。此外，TNC還與慢性炎癥、纖維化等疾病相關(guān)，顯示出其在多種生物學(xué)過程中的復(fù)雜角色。

熱銷產(chǎn)品

Recombinant Human Tenascin (TNC), partial (CSB-RP115094h(C))

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP115094h(C) could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) TNC.

TNC Antibody (CSB-PA11509A0Rb)

驗(yàn)證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA11509A0Rb at dilution of 1:50

TNC Antibody

TNC Protein

TNC ELISA Kit

TNC Antibodies

TNC for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA11504D0Rb	TNC Antibody, Biotin conjugated	Human	ELISA
CSB-PA11509C0Rb	TNC Antibody, FITC conjugated	Human
CSB-PA11509A0Rb	TNC Antibody	Human	ELISA, IHC
CSB-PA11504A0Rb	TNC Antibody	Human	ELISA, IHC
CSB-PA11509D0Rb	TNC Antibody, Biotin conjugated	Human	ELISA
CSB-PA11509B0Rb	TNC Antibody, HRP conjugated	Human	ELISA
CSB-PA006110	TNC Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA296975	TNC Antibody	Human,Mouse	ELISA,IHC

TNC Proteins

TNC Proteins for Gallus gallus (Chicken)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023954CH CSB-EP023954CH CSB-BP023954CH CSB-MP023954CH CSB-EP023954CH-B	Recombinant Chicken Tenascin (TNC), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNC Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP023954HU CSB-EP023954HU CSB-BP023954HU CSB-MP023954HU CSB-EP023954HU-B	Recombinant Human Tenascin (TNC), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-RP115094h(C)	Recombinant Human Tenascin (TNC), partial	E.coli

TNC Proteins for Sus scrofa (Pig)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-BP642747PI CSB-MP642747PI CSB-EP642747PI-B	Recombinant Pig Tenascin (TNC), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TNC Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP768917MO	Recombinant Mouse Tenascin (Tnc), partial	Yeast
CSB-EP768917MO CSB-EP768917MO-B	Recombinant Mouse Tenascin (Tnc), partial	E.coli In Vivo Biotinylation in E.coli
CSB-BP768917MO	Recombinant Mouse Tenascin (Tnc), partial	Baculovirus
CSB-MP768917MO	Recombinant Mouse Tenascin (Tnc), partial	Mammalian cell