TNFRSF11A
TNFRSF11A，即腫瘤壞死因子受體超家族成員11A，別名RANK、CD265、ODFR、sTNR11_HUMAN、TRANCE-R等。它是一種由TNFRSF11A基因編碼的蛋白質(zhì)，屬于腫瘤壞死因子受體家族，主要表達于破骨細胞、活化的T細胞和B細胞等。TNFRSF11A的作用機制主要是通過與其配體RANKL結(jié)合，激活下游的NF-κB和MAPK信號通路，從而促進破骨細胞的分化和活化，參與骨吸收過程。TNFRSF11A在骨代謝、免疫系統(tǒng)以及某些疾病的發(fā)生發(fā)展中具有重要意義，如與骨代謝疾病、自身免疫性疾病和某些癌癥的發(fā)展相關(guān)。
熱銷產(chǎn)品
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TNFRSF11A Antibody (CSB-PA925190)
驗證數(shù)據(jù)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human liver tissue, mouse kidney tissue, Primary antibody: CSB-PA925190(TNFRSF11A Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
TNFRSF11A Antibodies
TNFRSF11A for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA08467A0Rb | TNFRSF11A Antibody | Human | ELISA, WB, IF |
| CSB-PA925190 | TNFRSF11A Antibody | Human,Mouse | ELISA,WB |
TNFRSF11A Proteins
TNFRSF11A Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP023968MO1 CSB-EP023968MO1 CSB-BP023968MO1 CSB-MP023968MO1 CSB-EP023968MO1-B |
Recombinant Mouse Tumor necrosis factor receptor superfamily member 11A (Tnfrsf11a), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF023968MO | Recombinant Mouse Tumor necrosis factor receptor superfamily member 11A (Tnfrsf11a) | in vitro E.coli expression system |
TNFRSF11A Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-EP896933HU | Recombinant Human Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A), partial | E.coli |
| CSB-YP896933HU CSB-EP896933HU CSB-BP896933HU CSB-EP896933HU-B |
Recombinant Human Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP002321HU | Recombinant Human Tumor necrosis factor receptor superfamily member 11A protein (TNFRSF11A), partial (Active) | E.Coli |
| CSB-MP896933HU | Recombinant Human Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A), partial | Mammalian cell |
TNFRSF11A ELISA Kit
TNFRSF11A ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13539h | Human Soluble Receptor Activator of Nuclear Factor-kB,sRANK ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/ml |
