TREML2
TREML2，全稱為triggering receptor expressed on myeloid cells-like 2，別名包括CD336、NK-p44等。該蛋白屬于免疫球蛋白超家族，具有一個(gè)免疫球蛋白樣結(jié)構(gòu)域，表達(dá)于細(xì)胞表面。TREML2主要在免疫細(xì)胞中表達(dá)，如小膠質(zhì)細(xì)胞、巨噬細(xì)胞、樹(shù)突細(xì)胞等，并在免疫應(yīng)答中發(fā)揮重要作用。研究表明，TREML2可以與CD276相互作用，增強(qiáng)T細(xì)胞的活化，并參與炎癥反應(yīng)的調(diào)節(jié)。此外，TREML2還與多種疾病相關(guān)，包括阿爾茨海默病、肥胖癥、癌癥以及心血管疾病等。目前，針對(duì)TREML2的藥物研發(fā)正在積極開(kāi)展中，例如，有研究開(kāi)發(fā)了一種抗體轉(zhuǎn)運(yùn)載體（ATV）可以激活TREM2的藥物，用于治療阿爾茨海默病。
熱銷產(chǎn)品
TREML2 Antibody (CSB-PA729201LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA729201LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA729201LA01HU at dilution of 1:100
TREML2 Antibodies
TREML2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA729201LA01HU | TREML2 Antibody | Human | ELISA, IHC |
| CSB-PA729201LD01HU | TREML2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA729201LC01HU | TREML2 Antibody, FITC conjugated | Human | |
| CSB-PA729201LB01HU | TREML2 Antibody, HRP conjugated | Human | ELISA |
TREML2 Proteins
TREML2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP729201HU CSB-EP729201HU CSB-BP729201HU CSB-MP729201HU CSB-EP729201HU-B |
Recombinant Human Trem-like transcript 2 protein (TREML2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
