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TRIM72

TRIM72,全稱為Tripartite Motif Containing 72,是一種肌肉特異性蛋白,也被稱為Mitsugumin-53或Mg53。它在細(xì)胞膜修復(fù)中扮演重要角色,能夠修復(fù)受損的細(xì)胞膜,并參與細(xì)胞自噬過(guò)程。TRIM72與多種信號(hào)通路有關(guān),如胰島素受體信號(hào)通路和肌管分化的負(fù)調(diào)控。此外,TRIM72的異常與某些疾病相關(guān),如肌萎縮側(cè)索硬化(漸凍癥)。近年來(lái),針對(duì)TRIM72的藥物研發(fā)取得進(jìn)展,例如全球首款針對(duì)漸凍癥的基因治療藥物SNUG01,它通過(guò)遞送工程化TRIM72基因來(lái)修復(fù)受損的神經(jīng)元,為漸凍癥患者帶來(lái)了新的治療希望。

熱銷產(chǎn)品

Recombinant Human Tripartite motif-containing protein 72 (TRIM72), partial (CSB-EP744394HU)

驗(yàn)證數(shù)據(jù)

CSB-EP744394HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TRIM72 Antibody (CSB-PA080146)

驗(yàn)證數(shù)據(jù)

CSB-PA080146

Immunohistochemical analysis of paraffin-embedded Mouse PancreasTissue using TRIM72 Polyclonal Antibody.

CSB-PA080146

Western blot analysis of Mouse skeletal muscle using TRIM72 Polyclonal Antibody.

Human Tripartite motif-containing protein 72(TRIM72) ELISA kit (CSB-EL024511HU)

驗(yàn)證數(shù)據(jù)

CSB-EL024511HU 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-EL024511HU

規(guī)格:96T/48T

靈敏度:6.25 pg/mL

檢測(cè)范圍:25 pg/mL-1600 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TRIM72 Antibodies

TRIM72 for Homo sapiens (Human)

TRIM72 Proteins

TRIM72 Proteins for Homo sapiens (Human)

TRIM72 ELISA Kit

TRIM72 ELISA Kit for Homo sapiens (Human)