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TSC1

Hamartin is a protein in humans that is encoded by TSC1 gene. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

TSC1 Antibodies

TSC1 for Homo sapiens (Human)

TSC1 Proteins

TSC1 Proteins for Homo sapiens (Human)

TSC1 Proteins for Mus musculus (Mouse)