USP25
USP25，即泛素特異性肽酶25，別名USP21。它是一種去泛素化酶，屬于DUB（去泛素化酶）USP亞家族的重要成員。USP25在人類細胞中廣泛表達，尤其在心臟和骨骼肌中特異性表達，并在肌肉發(fā)生過程中上調。USP25的作用機制是通過其USP結構域與目標蛋白直接結合，去除K48泛素鏈，防止蛋白酶體途徑降解，從而維持蛋白質的穩(wěn)定性。USP25參與調節(jié)多種細胞過程，包括蛋白質穩(wěn)定性、細胞信號轉導和程序性細胞死亡。它與多種疾病相關，包括癌癥、神經退行性疾病、心血管疾病等。
熱銷產品
USP25 Antibody (CSB-PA883400LA01HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA883400LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA883400LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
USP25 Antibodies
USP25 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA025715GA01HU | USP25 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA883400LA01HU | USP25 Antibody | Human | ELISA, IHC, IF |
| CSB-PA883400LB01HU | USP25 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA883400LC01HU | USP25 Antibody, FITC conjugated | Human | |
| CSB-PA883400LD01HU | USP25 Antibody, Biotin conjugated | Human | ELISA |
USP25 Proteins
USP25 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP025715MO CSB-EP025715MO CSB-BP025715MO CSB-MP025715MO CSB-EP025715MO-B |
Recombinant Mouse Ubiquitin carboxyl-terminal hydrolase 25 (Usp25) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
USP25 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP883400HU CSB-EP883400HU CSB-BP883400HU CSB-MP883400HU CSB-EP883400HU-B |
Recombinant Human Ubiquitin carboxyl-terminal hydrolase 25 (USP25), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
