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YTHDF2

YTHDF2,別名DF2、CAHL、HGRG8、NY-REN-2。YTHDF2屬于YTH結(jié)構(gòu)域超家族成員,含有YTH結(jié)構(gòu)域,該結(jié)構(gòu)域通常位于蛋白質(zhì)序列的中間,與RNA結(jié)合。YTHDF2通過識別并結(jié)合N6-甲基腺苷(m6A)修飾的mRNA,調(diào)節(jié)這些mRNA的穩(wěn)定性和翻譯效率。YTHDF2在調(diào)控基因表達、mRNA代謝和細胞信號傳導(dǎo)中起重要作用。YTHDF2的功能異常與多種疾病相關(guān),包括急性髓性白血病、視網(wǎng)膜色素變性、Wilms瘤等。

熱銷產(chǎn)品

Recombinant Human YTH domain-containing family protein 2 (YTHDF2), partial (CSB-EP896902HU2)

驗證數(shù)據(jù)

CSB-EP896902HU2

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

YTHDF2 Antibody (CSB-PA896902LA01HU)

驗證數(shù)據(jù)

CSB-PA896902LA01HU

Western Blot
Positive WB detected in: Jurkat whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate
All lanes: YTHDF2 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 63, 57 kDa
Observed band size: 63, 50 kDa

CSB-PA896902LA01HU

Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA896902LA01HU at dilution of 1:100

CSB-PA896902LA01HU

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA896902LA01HU at dilution of 1:100

CSB-PA896902LA01HU

Immunofluorescent analysis of Hela cells using CSB-PA896902LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

YTHDF2 Antibodies

YTHDF2 for Homo sapiens (Human)

YTHDF2 Proteins

YTHDF2 Proteins for Homo sapiens (Human)