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  4. Bovine Transthyretin(TTR) ELISA kit

Bovine Transthyretin(TTR) ELISA kit

  • 中文名稱：
    牛運(yùn)甲狀腺素蛋白(TTR)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-EL025270BO
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥4200/￥3000
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    牛運(yùn)甲狀腺素蛋白(TTR)酶聯(lián)免疫試劑盒（CSB-EL025270BO）為競(jìng)爭(zhēng)法 ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的TTR含量。TTR（轉(zhuǎn)甲狀腺素蛋白）是一種血漿運(yùn)載蛋白。其基因突變可致蛋白構(gòu)象改變、聚集和沉積，引發(fā)ATTR淀粉樣變性病，危害神經(jīng)系統(tǒng)、心臟等。目前研究聚焦于穩(wěn)定TTR結(jié)構(gòu)、抑制聚集等機(jī)制，以開發(fā)針對(duì)性治療藥物。試劑盒檢測(cè)范圍為312.5 ng/mL-5000 ng/mL，該產(chǎn)品適用于牛類生理機(jī)制研究、疾病模型建立或營養(yǎng)代謝實(shí)驗(yàn)中TTR蛋白動(dòng)態(tài)變化的追蹤，為動(dòng)物科學(xué)、獸醫(yī)學(xué)及比較醫(yī)學(xué)領(lǐng)域的科研人員提供可靠的檢測(cè)工具，助力探索TTR在跨膜運(yùn)輸、能量代謝或組織特異性表達(dá)中的生物學(xué)功能。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    TTR ELISA Kit; Transthyretin ELISA Kit; Prealbumin ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Bos taurus (Bovine)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍：
    312.5 ng/mL-5000 ng/mL
  • 靈敏度：
    312.5 ng/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Cardiovascular
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Competitive
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of bovine TTR in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:100Average %95
    Range %91-97
    1:200Average %103
    Range %99-107
    1:400Average %98
    Range %93-103
    1:800Average %92
    Range %87-95
  • 回收率：
    The recovery of bovine TTR spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9994-104
    EDTA plasma (n=4)8984-96
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2Average
    50000.147 0.153 0.150
    25000.266 0.275 0.271
    12500.511 0.512 0.512
    6250.905 0.903 0.904
    312.51.674 1.787 1.731
    02.689 2.599 2.644
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Transthyretin family
  • 組織特異性：
    Detected in serum (at protein level).
  • 數(shù)據(jù)庫鏈接：

    KEGG: bta:280948

    STRING: 9913.ENSBTAP00000014585

    UniGene: Bt.207