Dog Interleukin-1 receptor antagonist protein(IL1RN) ELISA kit
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中文名稱:犬白介素1受體拮抗劑蛋白(IL1RN)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-EL011628DO
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規(guī)格:96T/48T
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價(jià)格:¥4200/¥3000
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:犬白介素1受體拮抗劑蛋白(IL1RN)酶聯(lián)免疫試劑盒(CSB-EL011628DO)為雙抗夾心法ELISA試劑盒,定量檢測(cè)血清、血漿、組織勻漿樣本中的IL1RN含量。IL1RN基因編碼白介素 - 1受體拮抗劑。其背景在于它可調(diào)節(jié)炎癥反應(yīng),避免過度炎癥。研究機(jī)制方面,它能競爭性結(jié)合白介素 - 1受體,阻斷白介素 - 1的生物學(xué)活性,在多種炎癥性疾病如類風(fēng)濕關(guān)節(jié)炎的發(fā)病機(jī)制和治療研究里備受關(guān)注。試劑盒檢測(cè)范圍為15.6 pg/ml-1000 pg/ml,本試劑盒的應(yīng)用場(chǎng)景涵蓋犬類炎癥性疾病模型研究、免疫調(diào)節(jié)機(jī)制探索以及藥效評(píng)價(jià)實(shí)驗(yàn)中IL1RN表達(dá)水平的動(dòng)態(tài)監(jiān)測(cè),例如通過檢測(cè)感染或免疫刺激后血清、組織中的IL1RN濃度變化,解析炎癥反應(yīng)與拮抗系統(tǒng)的相互作用。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名:IL1RNInterleukin-1 receptor antagonist protein ELISA Kit; IL-1RN ELISA Kit; IL-1ra ELISA Kit; IRAP ELISA Kit; IL1 inhibitor ELISA Kit
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縮寫:IL1RN
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Uniprot No.:
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種屬:Canis lupus familiaris (Dog) (Canis familiaris)
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樣本類型:serum, plasma, tissue homogenates
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檢測(cè)范圍:15.6 pg/ml-1000 pg/ml
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靈敏度:3.9 pg/ml
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長:450 nm
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研究領(lǐng)域:Others
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測(cè)定原理:quantitative
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測(cè)定方法:Sandwich
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數(shù)據(jù)處理:
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貨期:3-5 working days
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
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基因功能參考文獻(xiàn):
- This study showed that the IL-1Ra:IL-1beta protein ratio was negatively correlated with clinical severity in dogs with inflammatory bowel disease. PMID: 22483380
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亞細(xì)胞定位:Secreted.
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蛋白家族:IL-1 family
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數(shù)據(jù)庫鏈接:
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