Horse Albumin(Alb) ELISA Kit
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中文名稱:馬白蛋白酶聯(lián)免疫試劑盒
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貨號:CSB-E16205Hs
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規(guī)格:96T/48T
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價格:¥4200/¥3000
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:馬白蛋白酶聯(lián)免疫試劑盒(CSB-E16205Hs)為競爭法ELISA試劑盒,定量檢測血清、血漿樣本中的ALB含量。ALB(白蛋白)是人體血液中含量最多的蛋白質(zhì),主要功能是調(diào)節(jié)血漿膠體滲透壓,作為多種內(nèi)源分子的載體蛋白。研究顯示,ALB在肝癌治療中具有潛在作用,通過檢測肝癌細(xì)胞中ALB的表達(dá)水平,可識別出ALB低表達(dá)的肝癌株,并預(yù)測其可能對ALB激動劑治療有響應(yīng)。此外,知母作為一種中草藥,其活性成分可能通過調(diào)控PI3K/Akt/GSK-3β通路,減少Aβ生成,抑制Aβ相關(guān)蛋白的表達(dá),從而發(fā)揮抗阿爾茨海默病的作用。試劑盒檢測范圍為1.25 μg/mL-80 μg/mL,靈敏度為1.247 μg/mL。特別在炎癥反應(yīng)研究、組織修復(fù)機(jī)制探索以及代謝調(diào)控相關(guān)的基礎(chǔ)研究中具有應(yīng)用價值,為研究者提供可靠的實驗工具進(jìn)行生物標(biāo)志物篩選和蛋白功能研究。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名:ALBSerum albumin ELISA kit; allergen Equ c 3 ELISA kit
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縮寫:
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Uniprot No.:
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種屬:Equus caballus (Horse)
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樣本類型:serum, plasma
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檢測范圍:1.25 μg/mL-80 μg/mL
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靈敏度:1.247 μg/mL
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反應(yīng)時間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Metabolism
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測定原理:quantitative
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測定方法:Competitive
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數(shù)據(jù)處理:
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貨期:3-5 working days
相關(guān)產(chǎn)品
靶點詳情
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最新研究進(jìn)展:MAU(microalbuminuria)是指尿液中微量白蛋白的異常排出,通常作為腎病的早期標(biāo)志之一。最新研究表明,MAU與多種疾病相關(guān),包括糖尿病、高血壓和心血管疾病等。研究者們正在努力探索MAU與這些疾病之間的關(guān)系及其潛在機(jī)制,以期為預(yù)防和治療提供更有效的策略。
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功能:Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin.
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基因功能參考文獻(xiàn):
- the structural homology between HSA and ESA is big, their crystal complexes with Myr-2S-cPA demonstrate significantly different mode of binding of this LPL analogue. HSA binds three molecules of Myr-2S-cPA, whereas ESA only one. Moreover, none of the identified Myr-2S-cPA binding sites overlap in both albumins PMID: 27129297
- A crystallographic structural study allows identification of serum albumin fragments responsible for immunogenicity and the postulation of a mechanism for equine antigen-antibody recognition. PMID: 22993082
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亞細(xì)胞定位:Secreted.
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蛋白家族:ALB/AFP/VDB family
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組織特異性:Plasma.
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數(shù)據(jù)庫鏈接:
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