Horse Interleukin 8,IL-8 ELISA Kit
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中文名稱:馬白介素8(IL-8/CXCL8)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E14021Hs
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規(guī)格:96T/48T
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價(jià)格:¥3800/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:馬白介素8(IL-8/CXCL8)酶聯(lián)免疫試劑盒(CSB-E14021Hs)為雙抗夾心法ELISA試劑盒,定量檢測(cè)血清、血漿、組織勻漿樣本中的CXCL8含量。CXCL8 即趨化因子配體 8,是一種重要的細(xì)胞因子。在炎癥反應(yīng)等生理病理過(guò)程中扮演關(guān)鍵角色。其機(jī)制主要是與相應(yīng)受體結(jié)合,激活下游信號(hào)通路,招募中性粒細(xì)胞等免疫細(xì)胞至炎癥部位,在感染、腫瘤等疾病研究中受關(guān)注。試劑盒檢測(cè)范圍為15.6 pg/mL-1000 pg/mL,適用于細(xì)胞因子網(wǎng)絡(luò)研究、藥物作用機(jī)制探索、疾病模型評(píng)估等科研領(lǐng)域,可兼容常規(guī)實(shí)驗(yàn)室操作流程,為體外實(shí)驗(yàn)、動(dòng)物模型或臨床前研究提供可靠的IL - 8濃度檢測(cè)方案。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說(shuō)明書。
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別名:CXCL8 ELISA Kit; IL8 ELISA Kit; Interleukin-8 ELISA Kit; IL-8 ELISA Kit; C-X-C motif chemokine 8 ELISA Kit; Chemokine ELISA Kit; C-X-C motif) ligand 8 ELISA Kit
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縮寫:
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Uniprot No.:
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種屬:Equus caballus (Horse)
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樣本類型:serum, plasma, tissue homogenates
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檢測(cè)范圍:15.6 pg/mL-1000 pg/mL
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靈敏度:3.9 pg/mL
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Immunology
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測(cè)定原理:quantitative
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測(cè)定方法:Sandwich
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻(xiàn)
- Does antimicrobial therapy improve outcomes in horses with severe equine asthma and a positive tracheal wash bacterial culture? Husulak, Michelle L.et al,Canadian Journal of Veterinary Research,2018
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus.
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基因功能參考文獻(xiàn):
- Results suggested that chemokine expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses. PMID: 22280393
- Mapped six genes (EIF4G3, HSP90, RBBP6, IL8, TERT, and TERC) on the chromosomes of Equus caballus, Equus asinus, Equus grevyi, and Equus burchelli by fluorescence in situ hybridization. PMID: 21774619
- This study examined effects of in vitro exposure to solutions of hay dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction. PMID: 18052742
- These results suggest that MMP-1 and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon. PMID: 19552796
- The acute pulmonary neutrophilia characteristic of recurrent airway obstruction was not associated with an increase in expression of chemokines in pulmonary mononuclear cells from disease-susceptible horses. PMID: 19795943
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亞細(xì)胞定位:Secreted.
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蛋白家族:Intercrine alpha (chemokine CxC) family
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數(shù)據(jù)庫(kù)鏈接:
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