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  4. Human C-type lectin domain family 18 member A(CLEC18A) ELISA kit

Human C-type lectin domain family 18 member A(CLEC18A) ELISA kit

  • 中文名稱：
    人C型凝集素結(jié)構(gòu)域家族18成員A(CLEC18A)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-EL005521HU
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人C型凝集素結(jié)構(gòu)域家族18成員A(CLEC18A)酶聯(lián)免疫試劑盒（CSB-EL005521HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CLEC18A含量。試劑盒檢測范圍為0.312 ng/mL-20 ng/mL，適用于基礎(chǔ)科研領(lǐng)域中對(duì)CLEC18A表達(dá)調(diào)控機(jī)制的研究，例如通過血清或血漿樣本評(píng)估其在系統(tǒng)免疫中的動(dòng)態(tài)變化，或利用組織勻漿分析特定器官中該蛋白的分布特征。實(shí)驗(yàn)操作兼容常規(guī)實(shí)驗(yàn)室條件，可為免疫學(xué)、細(xì)胞信號(hào)通路及疾病模型研究提供可靠的數(shù)據(jù)支持，助力探索CLEC18A在生理病理過程中的分子作用。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    C-type lectin domain family 18 member A ELISA Kit; CL18A_HUMAN ELISA Kit; CLEC18A ELISA Kit; FLJ77955 ELISA Kit; Mannose receptor-like protein 2 ELISA Kit; MGC164804 ELISA Kit; Mrcl ELISA Kit; MRCL1 ELISA Kit; MRLP2 ELISA Kit
  • 縮寫：
    CLEC18A
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.312 ng/mL-20 ng/mL
  • 靈敏度：
    0.078 ng/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Others
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%      
    Three samples of known concentration were tested twenty times on one plate to assess.  
    Inter-assay Precision (Precision between assays): CV%<10%      
    Three samples of known concentration were tested in twenty assays to assess.    
                 
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human CLEC18A in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
      Sample Serum(n=4)  
    1:1 Average % 92  
    Range % 88-97  
    1:2 Average % 99  
    Range % 95-107  
    1:4 Average % 89  
    Range % 85-93  
    1:8 Average % 84  
    Range % 80-88  
  • 回收率：
    The recovery of human CLEC18A spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range  
    Serum (n=5) 100 95-107  
    EDTA plasma (n=4) 90 85-94  
                 
                 
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected  
    20 2.439 2.550 2.495 2.362  
    10 1.825 1.956 1.891 1.758  
    5 1.273 1.224 1.249 1.116  
    2.5 0.671 0.693 0.682 0.549  
    1.25 0.457 0.427 0.442 0.309  
    0.625 0.309 0.317 0.313 0.180  
    0.312 0.242 0.239 0.241 0.108  
    0 0.130 0.135 0.133    
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds polysaccharides in a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans.
  • 基因功能參考文獻(xiàn)：
    1. Plasma CLEC18 levels were correlated with the stage of HBV infection and could predict HBeAg loss and seroconversion in the patients with chronic hepatitis B (CHB) undergoing NUC therapy PMID: 30055605
  • 亞細(xì)胞定位：
    Secreted. Endoplasmic reticulum. Golgi apparatus. Endosome.
  • 組織特異性：
    Dectected in all cell lines tested and in peripheral blood cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30388

    OMIM: 616571

    KEGG: hsa:348174

    STRING: 9606.ENSP00000288040

    UniGene: Hs.592064