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  4. Human Oligodendrocyte-myelin glycoprotein(OMG) ELISA kit

Human Oligodendrocyte-myelin glycoprotein(OMG) ELISA kit

  • 中文名稱：
    人少突細(xì)胞髓磷脂糖蛋白(OMG)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-EL016334HU
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人少突細(xì)胞髓磷脂糖蛋白(OMG)酶聯(lián)免疫試劑盒（CSB-EL016334HU）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的OMG含量。試劑盒檢測(cè)范圍為0.156 ng/mL-10 ng/mL，適用于神經(jīng)科學(xué)基礎(chǔ)研究，如多發(fā)性硬化癥、腦白質(zhì)營(yíng)養(yǎng)不良等疾病模型的分子機(jī)制探索，亦可應(yīng)用于藥物開發(fā)中髓鞘修復(fù)相關(guān)化合物的體外效果評(píng)價(jià)。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    Oligodendrocyte-myelin glycoprotein ELISA Kit; Omg ELISA Kit; OMGP ELISA Kit; OMGP_HUMAN ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍：
    0.156 ng/mL-10 ng/mL
  • 靈敏度：
    0.039 ng/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Neuroscience
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human OMG in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %85
    Range %80-89
    1:2Average %97
    Range %92-102
    1:4Average %92
    Range %87-98
    1:8Average %98
    Range %94-102
  • 回收率：
    The recovery of human OMG spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 8884-92
    EDTA plasma (n=4)107102-112
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    102.645 2.534 2.590 2.452
    51.987 2.096 2.042 1.904
    2.51.238 1.345 1.292 1.154
    1.250.754 0.765 0.760 0.622
    0.6250.429 0.446 0.438 0.300
    0.3120.312 0.324 0.318 0.180
    0.1560.221 0.226 0.224 0.086
    00.137 0.138 0.138
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

引用文獻(xiàn)

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
  • 基因功能參考文獻(xiàn)：
    1. The results do not support a relationship between the OMGP gene and the learning disability phenotype observed in neurofibromatosis type 1. PMID: 21534343
    2. novel mutations and novel polymorphisms in coding regions and 5'UTR were detected in patients with with non-syndromic mental retardation PMID: 16425041
    3. Data show that oligodendrocyte-myelin glycoprotein is downregulated in schizophrenia anterior temporal lobe revealed by shotgun proteome analysis. PMID: 19034380
  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 組織特異性：
    Oligodendrocytes and myelin of the central nervous system.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8135

    OMIM: 164345

    KEGG: hsa:4974

    STRING: 9606.ENSP00000247271

    UniGene: Hs.113874