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  4. Human SPARC-related modular calcium-binding protein 2(SMOC2) ELISA kit

Human SPARC-related modular calcium-binding protein 2(SMOC2) ELISA kit

  • 中文名稱：
    人SPARC相關(guān)模塊化鈣結(jié)合蛋白2(SMOC2)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-EL021843HU
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人SPARC相關(guān)模塊化鈣結(jié)合蛋白2(SMOC2)酶聯(lián)免疫試劑盒（CSB-EL021843HU）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織培養(yǎng)上清液、組織勻漿樣本中的SMOC2含量。試劑盒檢測(cè)范圍為0.156 ng/mL-10 ng/mL，適用于科學(xué)研究中SMOC2的表達(dá)水平分析，如探索其在組織再生、疾病模型或細(xì)胞功能研究中的作用機(jī)制本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    bA270C4A.1 ELISA Kit; bA37D8.1 (secreted modular calcium binding protein 2) ELISA Kit; bA37D8.1 ELISA Kit; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein) ELISA Kit; dJ421D16.1 ELISA Kit; MST117 ELISA Kit; MSTP117 ELISA Kit; MSTP140 ELISA Kit; Secreted modular calcium binding protein 2 ELISA Kit; Secreted modular calcium-binding protein 2 ELISA Kit; SMAP 2 ELISA Kit; SMAP-2 ELISA Kit; SMAP2 ELISA Kit; SMOC 2 ELISA Kit; SMOC-2 ELISA Kit; SMOC2 ELISA Kit; SMOC2_HUMAN ELISA Kit; Smooth muscle associated protein 2 ELISA Kit; Smooth muscle-associated protein 2 ELISA Kit; SPARC related modular calcium binding 2 ELISA Kit; SPARC-related modular calcium-binding protein 2 ELISA Kit
  • 縮寫：
    SMOC2
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, cell culture supernates, tissue homogenates
  • 檢測(cè)范圍：
    0.156 ng/mL-10 ng/mL
  • 靈敏度：
    0.039 ng/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Cardiovascular
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human SMOC2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %97
    Range %92-103
    1:2Average %100
    Range %96-104
    1:4Average %93
    Range %87-97
    1:8Average %99
    Range %92-103
  • 回收率：
    The recovery of human SMOC2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9187-95
    EDTA plasma (n=4)9488-97
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/mlOD1OD2AverageCorrected
    102.272 2.211 2.242 2.094
    51.794 1.765 1.780 1.632
    2.51.190 1.123 1.157 1.009
    1.250.787 0.754 0.771 0.623
    0.6250.493 0.482 0.488 0.340
    0.3120.336 0.348 0.342 0.194
    0.1560.236 0.221 0.229 0.081
    00.149 0.147 0.148
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis.
  • 基因功能參考文獻(xiàn)：
    1. SMOC2 was highly expressed in both peritoneal and endometrioma lesions. Considering that the genes studied participate either directly or indirectly in cellular processes that can lead to cell migration, angiogenesis, and inappropriate invasion, it is possible that the deregulation of these genes caused the development and maintenance of ectopic tissue. PMID: 28678915
    2. The expression of Smoc2 was significantly higher in hepatocellular carcinoma (HCC) tissues compared with corresponding non-tumor liver tissues. Smoc2 promotes the proliferation of HCC cells through accelerating cell cycle progression. PMID: 28018113
    3. L1-mediated CRC progression involves the acquisition of a stem cell-like phenotype, and that SMOC-2 elevation is necessary for L1-mediated induction of more aggressive/invasive CRC properties. PMID: 25915847
    4. could not detect an association between SMOC2 gene and AMD. This study tests the candidacy of SMOC2 gene to the etiology of AMD PMID: 22964816
    5. SMOC2 SNP may play a role in autoimmune thyroid disease susceptibility as a dominant polymorphism. PMID: 23463390
    6. mutation in exon 8 of the SMOC2 gene linked to oligodontia PMID: 23317772
    7. Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects PMID: 22152679
    8. The variant rs13208776 in SMOC2 gene does not play a major role in increasing the risk of vitiligo in Jordanian Arab patients. PMID: 20965805
    9. SMOC2 is a risk locus for generalized vitiligo and perhaps other autoimmune diseases PMID: 19890347
    10. identification of gene, chromosome mapping PMID: 12741954
    11. SMOC-2 is a novel angiogenic factor that potentiates angiogenic effects of growth factors PMID: 16774925
    12. We tested association between SMOC2 polymorphisms and FEV(1) and FVC. SMOC2 might play an important role in the determination of FEV(1) and FVC PMID: 17204727
    13. Although this study specifies rat, the authors studied and discussed the human gene in this study as well. PMID: 12031507

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  • 相關(guān)疾?。?/div>
    Dentin dysplasia 1 (DTDP1)
  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix, basement membrane.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20323

    OMIM: 125400

    KEGG: hsa:64094

    STRING: 9606.ENSP00000346537

    UniGene: Hs.487200