搡老女人多毛老妇女中国,日韩亚洲欧美中文高清在线,人妻少妇一区二区三区,色妞色综合久久夜夜,日本熟妇xxxx

Your Good Partner in Biology Research

  1. 首頁
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Human WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1(WFIKKN1) ELISA kit

Human WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1(WFIKKN1) ELISA kit

  • 中文名稱：
    人WAP，kazal，免疫球蛋白，kunitz和NTR結(jié)構(gòu)域蛋白1(WFIKKN1)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL026098HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人WAP，kazal，免疫球蛋白，kunitz和NTR結(jié)構(gòu)域蛋白1(WFIKKN1)酶聯(lián)免疫試劑盒（CSB-EL026098HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的WFIKKN1含量。試劑盒檢測范圍為0.312 ng/mL-20 ng/mL，本試劑盒操作簡便，適用于科研領(lǐng)域中對WFIKKN1表達水平的定量分析，例如探索其在慢性炎癥性疾病、纖維化病變或腫瘤微環(huán)境中的潛在功能機制，也可用于評估不同實驗條件下該蛋白的動態(tài)變化。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    WFIKKN1 ELISA Kit; C16orf12 ELISA Kit; GASP2 ELISA Kit; WFIKKN ELISA Kit; PSEC0040 ELISA Kit; WAP ELISA Kit; Kazal ELISA Kit; immunoglobulin ELISA Kit; Kunitz and NTR domain-containing protein 1 ELISA Kit; Growth and differentiation factor-associated serum protein 2 ELISA Kit; GASP-2 ELISA Kit; hGASP-2 ELISA Kit; WAP ELISA Kit; follistatin ELISA Kit; immunoglobulin ELISA Kit; Kunitz and NTR domain-containing protein ELISA Kit
  • 縮寫：
    WFIKKN1
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.312 ng/mL-20 ng/mL
  • 靈敏度：
    0.078 ng/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Cell Biology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity.
  • 基因功能參考文獻：
    1. In this review, we summarize current knowledge about the WFIKKN proteins and propose that they are "companion" proteins for various growth factors by providing localized and sustained presentation of TGFB proteins to their respective receptors, thus regulating the balance between the activation of Smad and non-Smad pathways by TGFB. PMID: 27325460
    2. Data show that the KKN1 fragment generated by BMP1-cleavage of WFIKKN1 protein contributes most significantly to the observed enhancer activity. PMID: 27782377
    3. Data suggest that myostatin binding to its receptor (activin receptors type II) can be blocked by WFIKKN1 but not WFIKKN2; various forms of myostatin (promyostatin, myostatin pro-domain, and latent/processed myostatin) bind WFIKKN1 but not WFIKKN2. PMID: 23829672
    4. data indicate that WFIKKN proteins are antagonists of GDF8 and GDF11, but in the case of TGFbeta1, BMP2 and BMP4 they function as growth factor binding proteins PMID: 21054789
    5. Newly discovered WFIKKNPR gene structure and tissue distribution of gene expression is commpared with that of the WFIKKN gene in adult and fetal tissues and organs. PMID: 11928817
    6. Data suggest that the physiological target of WFIKKN protein may be trypsin. PMID: 12709070
    7. three-dimensional structure of a Kunitz domain with a tryptophan residue at the P02 site of the protease-recognition loop PMID: 16791741
    8. Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11. PMID: 18596030

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    WFIKKN family
  • 組織特異性：
    Expressed in pancreas, kidney, liver, placenta, and lung.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30912

    OMIM: 608021

    KEGG: hsa:117166

    STRING: 9606.ENSP00000324763

    UniGene: Hs.345818