Human anti-ganglioside (GM1)antibody(IgG)ELISA Kit
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中文名稱:人神經(jīng)節(jié)苷脂(GM1)抗體(IgG)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E09694h
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規(guī)格:96T/48T
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價(jià)格:¥3200/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:人神經(jīng)節(jié)苷脂(GM1)抗體(IgG)酶聯(lián)免疫試劑盒(CSB-E09694h)為間接法ELISA試劑盒,定性檢測血清樣本中的GM1 Ab (IgG)含量。GM1 Ab (IgG)即抗神經(jīng)節(jié)苷脂GM1抗體(IgG 型),其與多種神經(jīng)系統(tǒng)疾病相關(guān),如格林-巴利綜合征。研究機(jī)制上,該抗體可能攻擊神經(jīng)細(xì)胞膜上的 GM1 抗原,破壞神經(jīng)結(jié)構(gòu)和功能,導(dǎo)致神經(jīng)傳導(dǎo)異常,引發(fā)一系列神經(jīng)癥狀。研究者可通過該產(chǎn)品探究GM1抗體在神經(jīng)系統(tǒng)疾病模型中的表達(dá)規(guī)律,評(píng)估實(shí)驗(yàn)性治療方案對(duì)自身免疫反應(yīng)的調(diào)控作用,或在藥物開發(fā)中作為潛在生物標(biāo)志物的檢測工具。本產(chǎn)品為科研實(shí)驗(yàn)提供可靠的技術(shù)支持,廣泛應(yīng)用于基礎(chǔ)醫(yī)學(xué)、神經(jīng)生物學(xué)及藥理學(xué)研究領(lǐng)域。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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縮寫:GM1 Ab (IgG)
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種屬:Homo sapiens (Human)
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樣本類型:serum
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檢測范圍:Request Information
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靈敏度:Request Information
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測波長:450 nm
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研究領(lǐng)域:Neuroscience
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測定原理:qualitative
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測定方法:Indirect
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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標(biāo)準(zhǔn)曲線:
Test parameter
specification
test result
Positive control
>0.8
1.128
Negative control
<0.1
0.074
Positive rate
10,Positive
100%
Negative rate
10,Negative
100%
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貨期:3-5 working days
引用文獻(xiàn)
- Sialic Acid and Anti-ganglioside Antibody Levels in Children with Autism Spectrum Disorders Yang X.et al,Brain Res.,2017
- Analysis of serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barré syndrome Zhang LJ.et al,Clin Chim Acta.,2017
- Reduced soluble RAGE is associated with disease severity of axonal Guillain-Barr茅 syndrome. Zhang DQ.et al,Sci Rep.,2016
相關(guān)問答
I would like to know the specificty of this kit, does the kit detect anti-sialylated GM1 autoantibody or anti-asialo-GM1 autoantibody or both?
GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue.
We have no such detailed types for anti-sialylated GM1 autoantibody or anti-asialo-GM1 autoantibody.
As for this kit CSB-E09694h, it detects GM1 Ab (IgG).
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