Monkey Apolipoprotein(a) (LPA) ELISA kit
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中文名稱:猴載脂蛋白α(LPA)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-EL013044RH
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規(guī)格:96T/48T
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價(jià)格:¥4200/¥3000
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:猴載脂蛋白α(LPA)酶聯(lián)免疫試劑盒(CSB-EL013044RH)為競(jìng)爭(zhēng)法ELISA試劑盒,定量檢測(cè)血清、血漿、組織勻漿樣本中的LPA含量。猴載脂蛋白α(LPA)是一種與心血管疾病風(fēng)險(xiǎn)相關(guān)的蛋白質(zhì),其表達(dá)水平受基因調(diào)控。研究發(fā)現(xiàn),LPA通過(guò)其特定的結(jié)構(gòu)域與低密度脂蛋白(LDL)結(jié)合,形成脂蛋白(a)(Lp(a)),增加心血管疾病風(fēng)險(xiǎn)。目前,針對(duì)LPA的研究主要集中在開(kāi)發(fā)能夠抑制其表達(dá)或阻斷其與LDL結(jié)合的藥物,以降低心血管疾病風(fēng)險(xiǎn)。試劑盒檢測(cè)范圍為31.25 ng/mL-2000 ng/mL,適用于靈長(zhǎng)類動(dòng)物模型中脂代謝調(diào)控、心血管疾病機(jī)制、藥物干預(yù)效果評(píng)估等基礎(chǔ)研究,為科研人員提供穩(wěn)定可靠的LPA蛋白表達(dá)水平分析工具。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
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別名:LPAApolipoprotein(a ELISA kit; Apo(a) ELISA kit; Lp(a) ELISA kit; EC 3.4.21.- ELISA kit; Fragment ELISA kit
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縮寫(xiě):Lp-α, LPA
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Uniprot No.:
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種屬:Monkey
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樣本類型:serum, plasma, tissue homogenates
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檢測(cè)范圍:31.25 ng/mL-2000 ng/mL
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靈敏度:15.63 ng/mL
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Cardiovascular
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測(cè)定原理:quantitative
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測(cè)定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
標(biāo)準(zhǔn)曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. ng/ml OD1 OD2 Average 2000 0.159 0.157 0.158 1000 0.290 0.278 0.284 500 0.427 0.421 0.424 250 0.669 0.653 0.661 125 0.948 0.927 0.938 62.5 1.259 1.200 1.230 31.25 1.532 1.483 1.508 0 2.032 2.134 2.083 -
數(shù)據(jù)處理:
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貨期:3-5 working days
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.
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相關(guān)疾病:Elevated plasma concentrations of apo(a) and its naturally occurring proteolytic fragments are correlated with atherosclerosis. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.
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蛋白家族:Peptidase S1 family, Plasminogen subfamily
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數(shù)據(jù)庫(kù)鏈接:
STRING: 9544.ENSMMUP00000021286
UniGene: Mmu.3290
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