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  4. Monkey Insulin-like Growth Factor 1(IGF-1) ELISA KIT

Monkey Insulin-like Growth Factor 1(IGF-1) ELISA KIT

  • 中文名稱：
    猴胰島素樣生長因子1(IGF-1)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-E13401Mk
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥4200/￥3000
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    猴胰島素樣生長因子1(IGF-1)酶聯(lián)免疫試劑盒（CSB-E13401Mk）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿樣本中的IGF-1含量。IGF-1即胰島素樣生長因子-1，在人體生長、發(fā)育及代謝調(diào)節(jié)等過程有重要作用。其研究機(jī)制方面，主要通過與受體結(jié)合激活下游信號(hào)通路，參與細(xì)胞增殖、分化等過程。研究該靶點(diǎn)對(duì)生長發(fā)育相關(guān)疾病、癌癥等的防治有潛在價(jià)值。試劑盒檢測(cè)范圍為62.5 ng/mL-4000 ng/mL，該產(chǎn)品可支持靈長類動(dòng)物模型中IGF-1相關(guān)機(jī)制研究，例如探究生長激素軸調(diào)控、代謝性疾病模型建立、衰老相關(guān)研究或藥物干預(yù)實(shí)驗(yàn)中的生物標(biāo)志物動(dòng)態(tài)監(jiān)測(cè)，為發(fā)育生物學(xué)、內(nèi)分泌學(xué)及營養(yǎng)學(xué)領(lǐng)域的科研工作者提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    IGF1 ELISA Kit; Insulin-like growth factor I ELISA Kit; IGF-I ELISA Kit; Somatomedin ELISA Kit
  • 縮寫：
    IGF-1
  • Uniprot No.：
  • 種屬：
    Monkey
  • 樣本類型：
    serum, plasma
  • 檢測(cè)范圍：
    0.625 ng/ml-40 ng/ml
  • 靈敏度：
    0.312 ng/ml
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：

  • 標(biāo)準(zhǔn)曲線：

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

平均分:
5.0分 - 1 個(gè)評(píng)價(jià)

樣品類型：血清

樣品信息：其他 猴

稀釋比：1:50

產(chǎn)品評(píng)價(jià)： 靈敏度良好，洗液可以考慮多一些

By 張老師

相關(guān)問答

■ 常見問題解答
Q:

Can you please let me know if this kit was tested for Rhesus Monkey?

A:
Thanks for your inquiry.
CSB-E13401Mk
This kit is designed against Rhesus Monkey.
We tested undiluted serum and plasma samples before and the test value is 1000ng/ml.
Pls let me know if you have any further questions. Thank you.
Q:

Thanks for your response.
What is the dynamic range for concentration in standard protein calibration curve?

A:
Thanks for your inquiry.
I will send you the manual by e-mail.
The detection range of this kit is 62.5 ng/ml-4000 ng/ml.Pls let me know if you have any further questions. Thank you.

靶點(diǎn)詳情

  • 功能：
    The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1.
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Insulin family