Mouse Complement C1q tumor necrosis factor-related protein 6(C1QTNF6) ELISA kit
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中文名稱:小鼠補(bǔ)體C1q腫瘤壞死因子相關(guān)蛋白6(C1QTNF6)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-EL003651MO
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規(guī)格:96T/48T
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價(jià)格:¥3600/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:小鼠補(bǔ)體C1q腫瘤壞死因子相關(guān)蛋白6(C1QTNF6)酶聯(lián)免疫試劑盒(CSB-EL003651MO)檢測(cè)樣本中的C1QTNF6含量。C1QTNF6是一種與炎癥和代謝相關(guān)的基因,其表達(dá)與多種疾病如1型糖尿病、多囊卵巢綜合征等密切相關(guān)。研究顯示,C1QTNF6在相關(guān)疾病中的表達(dá)異??赡芡ㄟ^(guò)調(diào)節(jié)炎癥反應(yīng)和代謝途徑影響疾病進(jìn)程。該產(chǎn)品適用于基礎(chǔ)科研中探索C1QTNF6在代謝性疾病、慢性炎癥或癌癥發(fā)生發(fā)展中的作用機(jī)制,亦可用于評(píng)估藥物干預(yù)或基因編輯模型下靶蛋白的調(diào)控效果。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
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別名:C1qtnf6Complement C1q tumor necrosis factor-related protein 6 ELISA Kit
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縮寫(xiě):C1QTNF6
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Uniprot No.:
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種屬:Mus musculus (Mouse)
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檢測(cè)范圍:Request Information
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靈敏度:Request Information
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Others
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貨期:3-5 working days
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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基因功能參考文獻(xiàn):
- The results establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. PMID: 28726640
- CTRP6 knockdown down-regulated the levels of lipogenic genes and phosphorylated Erk1/2 (p-Erk1/2) in the early lipogenic stage, whereas up-regulated p-Erk1/2 in the terminal differentiation in skeletal myoblasts. PMID: 27125977
- CTRP6 specifically suppresses the alternative pathway of the complement system. C1qtnf6(-/-) mice are highly susceptible to induced arthritis, Arthus reaction, and experimental autoimmune encephalomyelitis. PMID: 26404464
- Knockdown of CTRP6 can inhibit adipogenesis of 3T3-L1 adipocytes through lipogenic marker genes and Erk1/2 signaling pathway. PMID: 25639984
- CTRP6 plays a role in fatty acid metabolism via the AMPK-ACC pathway. The globular domain of CTRP6 mediates the phosphorylation and activation of the 5'-AMP-activated protein kinase (AMPK) in skeletal muscle cells. PMID: 20102710
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亞細(xì)胞定位:Secreted.
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數(shù)據(jù)庫(kù)鏈接:
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