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Mouse Pancreatic Lipase(PL)ELISA Kit

  • 中文名稱:
    小鼠胰脂肪酶(PL)酶聯(lián)免疫試劑盒
  • 貨號:
    CSB-E16930m
  • 規(guī)格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品描述:
    小鼠胰脂肪酶(PL)酶聯(lián)免疫試劑盒(CSB-E16930m)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的PL含量。小鼠胰脂肪酶(PL)是胰腺分泌的一種消化酶,參與脂肪的消化和吸收。其表達與肥胖等代謝性疾病密切相關,成為研究肥胖和代謝性疾病機制的重要靶點。通過研究PL的功能和調(diào)控,有助于開發(fā)治療肥胖和相關代謝性疾病的藥物。試劑盒檢測范圍為62.5 mU/mL-4000 mU/mL,適用于科研場景中評估小鼠模型胰腺外分泌功能、脂質(zhì)代謝異常機制研究,或用于營養(yǎng)學、肥胖癥及藥物干預實驗中胰脂肪酶動態(tài)變化的監(jiān)測本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名:
    PnlipPancreatic triacylglycerol lipase ELISA Kit; PL ELISA Kit; PTL ELISA Kit; Pancreatic lipase ELISA Kit; EC 3.1.1.3 ELISA Kit
  • 縮寫:
    PL
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    62.5 mU/mL-4000 mU/mL
  • 靈敏度:
    15.6 mU/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Metabolism
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 數(shù)據(jù)處理:
  • 貨期:
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能:
    Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
  • 基因功能參考文獻:
    1. the ability to degrade unfolded protein decreases in the aging pancreas, and this leads to reduction of pancreatic lipase activity and a decrease in lipid absorption PMID: 25033985
    2. pancreatic triglyceride lipase has a critical role in dietary cholesterol absorption and a minimal role in dietary fat absorption in mice PMID: 12915407
    3. PTL and CEL serve complementary functions, working together to mediate the absorption of a major portion of dietary fat and fat-soluble vitamin esters PMID: 17604277
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    AB hydrolase superfamily, Lipase family
  • 組織特異性:
    Pancreas.
  • 數(shù)據(jù)庫鏈接: