Mouse Progesterone,PROG ELISA Kit
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中文名稱:小鼠孕激素/孕酮(PROG)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E05104m
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規(guī)格:96T/48T
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價(jià)格:¥3800/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:小鼠孕激素/孕酮(PROG)酶聯(lián)免疫試劑盒(CSB-E05104m)為競(jìng)爭(zhēng)法ELISA試劑盒,定量檢測(cè)血清、血漿樣本中的PROG含量。小鼠孕激素/孕酮(PROG)在妊娠和生殖過(guò)程中發(fā)揮關(guān)鍵作用,調(diào)控子宮內(nèi)膜和胎盤發(fā)育,維持妊娠穩(wěn)定。其作用機(jī)制涉及調(diào)節(jié)基因表達(dá)、影響細(xì)胞增殖和凋亡,并與孕酮受體結(jié)合,參與激素信號(hào)傳導(dǎo)。試劑盒檢測(cè)范圍為0.3 ng/mL-10 ng/mL,靈敏度為0.2 ng/mL。適用于生殖生物學(xué)、內(nèi)分泌調(diào)控機(jī)制研究及藥物/化合物對(duì)生殖系統(tǒng)影響的評(píng)估,例如探究妊娠動(dòng)物模型激素動(dòng)態(tài)、卵巢功能異常研究或激素替代治療相關(guān)實(shí)驗(yàn)。支持科研人員高效開展小鼠生殖健康、代謝調(diào)控等領(lǐng)域的基礎(chǔ)研究。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說(shuō)明書。
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縮寫:PROG
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種屬:Mus musculus (Mouse)
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樣本類型:serum, plasma
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檢測(cè)范圍:0.3 ng/mL-10 ng/mL
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靈敏度:0.2 ng/mL
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Signal Transduction
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測(cè)定原理:quantitative
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測(cè)定方法:Competitive
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精密度:
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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線性度:
To assess the linearity of the assay, samples were spiked with high concentrations of mouse PROG in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
Sample
Serum(n=4)
1:1
Average %
96
Range %
92-104
1:2
Average %
93
Range %
91-97
1:4
Average %
102
Range %
98-106
1:8
Average %
87
Range %
82-94
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回收率:
The recovery of mouse PROG spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
Sample Type
Average % Recovery
Range
Serum (n=5)
94
90-97
EDTA plasma (n=4)
89
85-94
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標(biāo)準(zhǔn)曲線:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ng/ml
OD1
OD2
Average
10
0.175
0.189
0.182
5
0.452
0.456
0.454
2.5
0.759
0.783
0.771
0.86
1.175
1.251
1.213
0.3
1.647
1.685
1.666
0
2.085
2.130
2.107
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數(shù)據(jù)處理:
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貨期:3-5 working days
引用文獻(xiàn)
- Afamin Ameliorates Testosterone Propionate (TP)-Induced Oxidative Stress and Mitochondrial Damage in Human Ovarian Granulosa Tumor Cells (KGN) by Upregulating the Expression of SIRT1 YL Ma, ZW Li, Z Wang, AJ Yang,Molecular Biology,2024
- High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis J Wen, Y Feng, L Xue, S Yuan, Q Chen, A Luo,Gut Microbes,2024
- DCAF2 is essential for the development of uterine epithelia and mouse fertility M Yang, K Wang, L Zhang, H Zhang,Frontiers in Cell and Developmental Biology,2024
- Integrated Single-Cell and Spatial Transcriptomics Reveal Microenvironment Disruptions by Androgen in Mouse Ovary M Luo, X Yang, M Zhou, J Zhang, B Yu, H Lian, J Ye,iScience,2024
- Placenta-derived SOD3 deletion impairs maternal behavior via alterations in FGF/FGFR-prolactin signaling axis Y Xu, AB Alves-Wagner, H Inada, SD Firouzjah,Cell Reports,2024
- Environmental exposure to cadmium impairs fetal growth and placental angiogenesis via GCN-2-mediated mitochondrial stress YW Xionga, XF Xuc, HL Zhua, XL Caoa, SJ Yia,J Hazard Mater,2020
- Preserving Fertility: Minimizing Ovarian Lymphatic Drainage Disruption in Gynecological Cancer Surgeries D Chen,/,2024
- Rfamide-Related Peptide-3 (RFRP-3) Receptor Gene is Expressed in Mouse Ovarian Granulosa Cells: Potential Role of RFRP-3 in Steroidogenesis and Apoptosis X Guo,/,2023
- FUNDC1-mediated mitophagy triggered by mitochondrial ROS is partially involved in 1-nitropyrene-evoked placental progesterone synthesis inhibition and intrauterine growth retardation in mice J Li,The Science of the total environment,2023
- Ovary-derived Decellularized Extracellular Matrix-based Bioink for Fabricating 3D Primary Ovarian Cells-laden Structures for Mouse Ovarian Failure Correction J Zheng,International Journal of Bioprinting,2023
- Activation of Atg5-dependent placental lipophagy ameliorates cadmium-induced fetal growth restriction YF Zhang,Environmental pollution,2023
- High Housing Density-Induced Chronic Stress Diminishes Ovarian Reserve via Granulosa Cell Apoptosis by Angiotensin II Overexpression in Mice J Kim,International journal of molecular sciences,2022
- Anti-Müllerian Hormone Inhibits FSH-Induced Cumulus Oocyte Complex In Vitro Maturation and Cumulus Expansion in Mice X Yu,Animals,2022
- Effects of the maternal gut microbiome and gut-placental axis on melatonin efficacy in alleviating cadmium-induced fetal growth restriction H Zhang,Ecotoxicology and environmental safety,2022
- Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice Dacheng Yang,Journal of Hazardous Materials,2022
- Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice Dacheng Yang,Journal of Hazardous Materials,2021
- Single-cell transcriptome and cell-specific network analysis reveal the reparative effect of neurotrophin-4 in preantral follicles grown in vitro Y Gu,Reproductive Biology and Endocrinology,2021
- In Situ Gene Therapy Rescues Doxorubicin-induced Ovarian Damage via Adenovirus Mediated Sirt1 and Tgfbr2 L Ma,Research Square,2021
- Uterine Insulin Sensitivity Defects Induced Embryo Implantation Loss Associated with Mitochondrial Dysfunction-Triggered Oxidative Stress Meixia Chen,Oxidative medicine and cellular longevity,2021
- Uterine Insulin Sensitivity Defects Induced Embryo Implantation Loss Associated with Mitochondrial Dysfunction-Triggered Oxidative Stress M Chen,Oxidative Medicine and Cellular Longevity,2021
- Methotrexate Therapy Promotes Cell Coverage and Stability in in-Stent Neointima X Liu,Cardiovascular Drugs and Therapy,2021
- Environmental exposure to cadmium impairs fetal growth and placental angiogenesis via GCN-2-mediated mitochondrial stress YW Xiong,Journal of Hazardous Materials,2020
- Potential of Auraptene in Improvement of Oocyte Maturation, Fertilization Rate, and Inflammation in Polycystic Ovary Syndrome Mouse Model M Abizadeh,Reproductive Sciences,2020
- Maternal cadmium exposure during late pregnancy causes fetal growth restriction via inhibiting placental progesterone synthesis Yong-Wei Xiong, et al,Ecotoxicology and Environmental Safety,2019
- Hashimoto’s thyroiditis impairs embryo implantation by compromising endometrial morphology and receptivity markers in euthyroid mice Wu Z, et al,Reproductive Biology and Endocrinology,2019
- Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice Liu J.et al,Environ Sci Pollut Res Int,2017
- Bisphenol A Initiates Excessive Premature Activation of Primordial Follicles in Mouse Ovaries via the PTEN Signaling Pathway Hu Y.et al,Reprod Sci.,2017
- Anthrax Toxin Receptor 2 Functions in ECM Homeostasis of the Murine Reproductive Tract and Promotes MMP Activity Reeves CV et al ,PLOS ONE,2012
- Superovulation Induced Changes of Lipid Metabolism in Ovaries and Embryos and Its Probable Mechanism Wang LY. et al,PLoS One,2015
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靶點(diǎn)詳情
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最新研究進(jìn)展:孕激素是一種女性激素,在女性生殖系統(tǒng)中起著調(diào)節(jié)各種生理過(guò)程的重要作用,通過(guò)與孕激素受體結(jié)合發(fā)揮作用。除了在懷孕和生殖周期中的重要性外,最近的研究表明孕激素在其他生物學(xué)過(guò)程中也扮演著至關(guān)重要的角色。例如,它參與調(diào)節(jié)神經(jīng)元生長(zhǎng)和再生、腦損傷后的神經(jīng)再生、記憶和認(rèn)知功能,并在中樞神經(jīng)系統(tǒng)中發(fā)揮重要作用。此外,孕激素還具有多種作用,如抗抑郁、抗焦慮、抗炎和抗腫瘤等。
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