Mouse Soluble Cluster of differentiation 30 ligand,sCD30L ELISA Kit
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中文名稱:小鼠可溶性CD30配體(sCD30L)酶聯(lián)免疫試劑盒
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貨號(hào):CSB-E04715m
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規(guī)格:96T/48T
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價(jià)格:¥3200/¥2500
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:小鼠可溶性CD30配體(sCD30L)酶聯(lián)免疫試劑盒(CSB-E04715m)為雙抗夾心法ELISA試劑盒,定量檢測(cè)血清、血漿、組織勻漿樣本中的TNFSF8含量。TNFSF8是重要靶點(diǎn)。它屬腫瘤壞死因子超家族,參與免疫調(diào)節(jié)。探索它與免疫細(xì)胞相互作用及信號(hào)傳導(dǎo)過(guò)程,期望通過(guò)調(diào)控它治療腫瘤、自身免疫病等,為開發(fā)新療法提供理論依據(jù)和方向。試劑盒檢測(cè)范圍為15.6 pg/mL-1000 pg/mL,適用于評(píng)估感染、自身免疫疾病等實(shí)驗(yàn)?zāi)P椭衧CD30L的表達(dá)調(diào)控,為研究T細(xì)胞活化、淋巴組織發(fā)育及免疫相關(guān)疾病機(jī)制提供可靠工具。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書。
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別名:Tnfsf8; Cd30l; Cd30lg; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD antigen CD153
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縮寫:
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Uniprot No.:
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種屬:Mus musculus (Mouse)
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樣本類型:serum, plasma, tissue homogenates
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檢測(cè)范圍:0.156 ng/ml - 10 ng/ml
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靈敏度:0.039 ng/ml
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反應(yīng)時(shí)間:1-5h
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樣本體積:50-100ul
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檢測(cè)波長(zhǎng):450 nm
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研究領(lǐng)域:Others
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貨期:3-5 working days
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能:Cytokine that binds to TNFRSF8/CD30. Induces proliferation of T-cells.
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基因功能參考文獻(xiàn):
- Altered expression of CD30L and IL-3 may be potential biomarkers for hepatotoxicity induced by D. bulbifera. PMID: 24647110
- It is shown here that CD30L knock out (KO) mice are highly susceptible to primary infection with Listeria monocytogenes as assessed by the survival rate. PMID: 21699557
- Modulation of CD30L/CD30 signaling by soluble CD30 could be a novel biological therapy for inflammatory diseases associated with Th17 responses. PMID: 21068411
- Characterization of the murine CD30 ligand (CD153) gene: gene structure and expression. PMID: 12392508
- CD30L is required for generation of long-lived memory CD8+ T cells; CD30L signaling triggers homing receptors for T(central memory) cells. PMID: 16177108
- Signaling executed by CD30positive T cell interaction with CD30Lpositive T cells plays a critical role in amplification of T helper type (Th)1 responses able to produce interferon-gamma against Mycobacterium bovis bacillus Calmette-Guerin infection. PMID: 18941223
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亞細(xì)胞定位:Membrane; Single-pass type II membrane protein.
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蛋白家族:Tumor necrosis factor family
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數(shù)據(jù)庫(kù)鏈接:
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