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  4. Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

Mouse cross linked C-telopeptide of type I collagen (CTX-Ⅰ) ELISA Kit

  • 中文名稱：
    小鼠Ⅰ型膠原C端肽(CTX-Ⅰ)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-E12782m
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    小鼠Ⅰ型膠原C端肽(CTX-Ⅰ)酶聯(lián)免疫試劑盒（CSB-E12782m）為競(jìng)爭(zhēng)法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿.樣本中的CTX-Ⅰ含量。CTX-Ⅰ，即Ⅰ型膠原C端肽，是膠原蛋白分解代謝的關(guān)鍵產(chǎn)物，其濃度變化反映骨基質(zhì)降解活性，常用于骨代謝異常、骨質(zhì)疏松模型研究及骨相關(guān)疾病的機(jī)制探索。研究機(jī)制涉及CTX-Ⅰ在骨吸收過程中的生成和作用，以及與骨代謝相關(guān)疾病的關(guān)系。試劑盒檢測(cè)范圍為0.23 ng/ml-15 ng/ml.，CTX - Ⅰ是Ⅰ型膠原蛋白分解代謝的關(guān)鍵產(chǎn)物，其濃度變化可反映骨基質(zhì)降解活性，常用于骨代謝異常、骨質(zhì)疏松模型研究及骨相關(guān)疾病的機(jī)制探索?？蒲袌?chǎng)景中可用于評(píng)估骨吸收標(biāo)志物水平，例如在骨質(zhì)疏松動(dòng)物模型中動(dòng)態(tài)監(jiān)測(cè)骨質(zhì)流失程度，或結(jié)合藥物干預(yù)實(shí)驗(yàn)探究骨代謝調(diào)控機(jī)制。支持科研人員高效完成骨代謝相關(guān)的基礎(chǔ)研究與藥效評(píng)價(jià)。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說(shuō)明書。
  • 別名：
    cross linked C-telopeptide of type 1 collagen (CTX-1),_x000D_cross linked C-telopeptide of type I collagen (CTX-I)
  • 縮寫：
    CTX-Ⅰ
  • 種屬：
    Mus musculus (Mouse)
  • 樣本類型：
    serum, plasma, tissue homogenates.
  • 檢測(cè)范圍：
    0.23 ng/ml-15 ng/ml.
  • 靈敏度：
    0.12 ng/ml.
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Others
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Competitive
  • 精密度：

    Intra-assay Precision (Precision within an assay): CV%<8%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<10%

    Three samples of known concentration were tested in twenty assays to assess.

  • 線性度：

    To assess the linearity of the assay, samples were spiked with high concentrations of mouse CTX-Ⅰ in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

    　

    Sample

    Serum(n=4)

    1:1

    Average %

    84

    Range %

    80-92

    1:2

    Average %

    87

    Range %

    81-94

    1:4

    Average %

    88

    Range %

    82-95

    1:8

    Average %

    93

    Range %

    86-98

  • 回收率：

    The recovery of mouse CTX-Ⅰ spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

    Sample Type

    Average % Recovery

    Range

    Serum (n=5)

    85

    81-91

    EDTA plasma (n=4)

    87

    82-93

  • 標(biāo)準(zhǔn)曲線：

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

    ng/ml

    OD1

    OD2

    Average

    15

    0.195

    0.204

    0.200

    7.5

    0.246

    0.260

    0.253

    3.75

    0.339

    0.348

    0.344

    1.87

    0.518

    0.529

    0.524

    0.94

    0.851

    0.841

    0.846

    0.47

    1.272

    1.253

    1.262

    0.23

    1.838

    1.784

    1.811

    0

    2.512

    2.525

    2.518

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

引用文獻(xiàn)

產(chǎn)品評(píng)價(jià)

相關(guān)問答

■ 常見問題解答
Q:

What's the antibody information of this kit?

A:
Thanks for your inquiry. Pls check our information: CSB-E12782m: Coated anti. Goat against rabbit secondary antibody; Specific anti: Rabbit polyclonal antibody
Coated anti. Goat against rabbit secondary antibody; Antigen Specific anti: Rabbit polyclonal antibody. Pls let me know if you have any further questions. Thank you.

靶點(diǎn)詳情

  • 最新研究進(jìn)展：
    Ⅰ型膠原交聯(lián)脫氨酸肽（CTX-Ⅰ）是膠原蛋白分解產(chǎn)物之一，它被認(rèn)為是骨吸收的生物標(biāo)志物之一。CTX-Ⅰ的檢測(cè)可以用于評(píng)估骨吸收水平，是一種廣泛應(yīng)用的臨床診斷指標(biāo)。最近的研究表明，CTX-Ⅰ還與一些非骨代謝方面的疾病有關(guān)，例如心血管疾病、糖尿病、腎臟疾病等。