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  4. Pig C-reactive protein,CRP ELISA Kit

Pig C-reactive protein,CRP ELISA Kit

  • 中文名稱：
    豬C反應(yīng)蛋白(CRP)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-E08163p
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥4200/￥3000
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    豬C反應(yīng)蛋白(CRP)酶聯(lián)免疫試劑盒（CSB-E08163p）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CRP含量。C反應(yīng)蛋白（CRP）是一種由肝臟在炎癥反應(yīng)中合成的急性期血清蛋白，能夠與肺炎球菌的C多糖反應(yīng)。CRP屬于五聚體蛋白，主要功能包括促進(jìn)細(xì)菌凝集、細(xì)菌莢膜腫脹、吞噬作用和補體固定。CRP作為炎癥標(biāo)志物，在細(xì)菌感染、炎癥過程和組織損傷的監(jiān)測中具有重要價值。試劑盒檢測范圍為0.625 ng/mL-40 ng/mL，該產(chǎn)品適用于動物模型研究、免疫調(diào)控機制探索或疫苗/藥物療效評價等科研場景，尤其可為豬類疾病的炎癥相關(guān)研究（如感染性疾病模型構(gòu)建、應(yīng)激反應(yīng)監(jiān)測）提供可靠的數(shù)據(jù)支持本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    CRP ELISA kit; PTX1C-reactive protein ELISA kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Sus scrofa (Pig)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測范圍：
    0.625 ng/mL-40 ng/mL
  • 靈敏度：
    0.156 ng/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Immunology
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：

  • 線性度：

  • 回收率：

  • 標(biāo)準(zhǔn)曲線：

  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 功能：
    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • 基因功能參考文獻(xiàn)：
    1. Enhanced external counterpulsation decreased C-reactive protein and increased flow-mediated dilation in hypercholesterolemia. PMID: 22681602
    2. serum C-reactive protein correlates with macrophage accumulation and coronary artery disease in hypercholesterolemic pigs PMID: 12754176
    3. CRP inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H oxidase via p38 kinase activation. PMID: 15718491
    4. The present study shows that elevated levels of serum CRP and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS. (postweaning multisystemic wasting syndrome) PMID: 16817761
    5. These data suggest that CRP might play a pathogenic role in the development of myointimal hyperplasia in polytetrafluoroethylene grafts. PMID: 17510097
    6. myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP PMID: 19036073
    7. CRP stimulates superoxide production and the subsequent formation of peroxynitrite from basal released nitric oxide compromises PGI(2) synthesis. PMID: 19410579
    8. Data show that during posttranplant obliterative bronchiolitis development, CRP is localized in inflammatory cells, myofibroblasts and endothelial cells probably as a part of the local inflammatory response. PMID: 19503785

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  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Pentraxin family
  • 組織特異性：
    Found in plasma.
  • 數(shù)據(jù)庫鏈接：