Rat Alpha-1-antitrypsin(SERPINA1) ELISA kit
-
中文名稱:大鼠α1-抗胰蛋白酶(SERPINA1)酶聯(lián)免疫試劑盒
-
貨號(hào):CSB-EL021053RA
-
規(guī)格:96T/48T
-
價(jià)格:¥3600/¥2500
-
其他:
產(chǎn)品詳情
-
產(chǎn)品描述:大鼠α1-抗胰蛋白酶(SERPINA1)酶聯(lián)免疫試劑盒(CSB-EL021053RA)為競(jìng)爭(zhēng)法ELISA試劑盒,定量檢測(cè)血清、血漿、組織勻漿樣本中的SERPINA1含量。SERPINA1是重要靶點(diǎn),其編碼的α1 - 抗胰蛋白酶可抑制多種蛋白酶活性。研究發(fā)現(xiàn)它與肺部疾病、肝臟疾病等密切相關(guān),機(jī)制可能是其異常導(dǎo)致蛋白酶 - 抗蛋白酶失衡,引發(fā)組織損傷,目前圍繞它的治療研究在積極開展。試劑盒檢測(cè)范圍為62.5 ng/mL-4000 ng/mL,適用于科研領(lǐng)域中對(duì)肝臟功能、炎癥反應(yīng)或代謝異常相關(guān)機(jī)制的研究,例如肝損傷模型評(píng)估、蛋白酶 - 抗蛋白酶系統(tǒng)平衡分析,以及藥物干預(yù)實(shí)驗(yàn)中的生物標(biāo)志物檢測(cè),為相關(guān)基礎(chǔ)研究和生物醫(yī)學(xué)探索提供可靠工具。本品僅用于科研,不用于臨床診斷,產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說(shuō)明書。
-
別名:Serpina1Alpha-1-antiproteinase ELISA kit; Alpha-1-antitrypsin ELISA kit; Alpha-1-proteinase inhibitor ELISA kit; Serpin A1 ELISA kit
-
縮寫:
-
Uniprot No.:
-
種屬:Rattus norvegicus (Rat)
-
樣本類型:serum, plasma, tissue homogenates
-
檢測(cè)范圍:62.5 ng/mL-4000 ng/mL
-
靈敏度:15.6 ng/mL
-
反應(yīng)時(shí)間:1-5h
-
樣本體積:50-100ul
-
檢測(cè)波長(zhǎng):450 nm
-
研究領(lǐng)域:Cardiovascular
-
測(cè)定原理:quantitative
-
測(cè)定方法:Competitive
-
數(shù)據(jù)處理:
-
貨期:3-5 working days
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能:Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.
-
基因功能參考文獻(xiàn):
- A1AT bidirectional uptake and secretion from lung endothelial cells towards the alveolar epithelium and airspaces PMID: 24743137
- These results suggest that transfer of the N-terminal acidic extension of HCII to alpha1-PI M358R enhanced its inhibition of thrombin by conferring the ability to bind exosite 1 on HAPI M358R. PMID: 16981704
-
亞細(xì)胞定位:Secreted.
-
蛋白家族:Serpin family
-
組織特異性:Plasma.
-
數(shù)據(jù)庫(kù)鏈接:
Most popular with customers
-
Human Transforming Growth factor β1,TGF-β1 ELISA kit
Detect Range: 23.5 pg/ml-1500 pg/ml
Sensitivity: 5.8 pg/ml
-
-
-
Mouse Tumor necrosis factor α,TNF-α ELISA Kit
Detect Range: 7.8 pg/ml-500 pg/ml
Sensitivity: 1.95 pg/ml
-
-
-
-